Lauschke VM - Search Results

1

Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention.

Youhanna S, Kemas AM, Wright SC, Zhong Y, Klumpp B, Klein K, Motso A, Michel M, Ziegler N, Shang M, Sabatier P, Kannt A, Sheng H, Oliva-Vilarnau N, Büttner FA, Seashore-Ludlow B, Schreiner J, Windbergs M, Cornillet M, Björkström NK, Hülsmeier AJ, Hornemann T, Olsen JV, Wang Y, Gramignoli R, Sundström M, Lauschke VM. Youhanna S, et al. Among authors: lauschke vm. Adv Sci (Weinh). 2024 Nov 28:e2407572. doi: 10.1002/advs.202407572. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39605182

2

PharmFreq: a comprehensive atlas of ethnogeographic allelic variation in clinically important pharmacogenes.

Tremmel R, Zhou Y, Camara MD, Laarif S, Eliasson E, Lauschke VM. Tremmel R, et al. Among authors: lauschke vm. Nucleic Acids Res. 2024 Nov 14:gkae1016. doi: 10.1093/nar/gkae1016. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39540424

3

Corrigendum to Incorporating new approach methodologies into regulatory nonclinical pharmaceutical safety assessment.

Turner J, Pound P, Owen C, Hutchinson I, Hop M, Chau DYS, Barrios Silva LV, Coleman M, Dubourg A, Harries LW, Hutter V, Kenna JG, Lauschke VM, Neuhaus W, Roper C, Watkins PB, Welch J, Rego Avarez L, Taylor K. Turner J, et al. Among authors: lauschke vm. ALTEX. 2024;41(4):674-675. doi: 10.14573/altex.2408291. ALTEX. 2024. PMID: 39484727 Free article.

4

The 75-Year Anniversary of the Department of Physiology and Pharmacology at Karolinska Institutet-Examples of Recent Accomplishments and Future Perspectives.

Weitzberg E, Ingelman-Sundberg M, Lundberg JO, Engberg G, Schulte G, Lauschke VM. Weitzberg E, et al. Among authors: lauschke vm. Pharmacol Rev. 2024 Oct 16;76(6):1089-1101. doi: 10.1124/pharmrev.124.001433. Pharmacol Rev. 2024. PMID: 39414365 Review.

5

The phage anti-restriction induced system: new insights into bacterial immunity and bacteriophage escape strategies.

Zhong Y, Lauschke VM. Zhong Y, et al. Among authors: lauschke vm. Signal Transduct Target Ther. 2024 Oct 5;9(1):269. doi: 10.1038/s41392-024-01995-x. Signal Transduct Target Ther. 2024. PMID: 39369022 Free PMC article. No abstract available.

6

Deep learning large-scale drug discovery and repurposing.

Yu M, Li W, Yu Y, Zhao Y, Xiao L, Lauschke VM, Cheng Y, Zhang X, Wang Y. Yu M, et al. Among authors: lauschke vm. Nat Comput Sci. 2024 Aug;4(8):600-614. doi: 10.1038/s43588-024-00679-4. Epub 2024 Aug 21. Nat Comput Sci. 2024. PMID: 39169261

7

The involvement of the Stat1/Nrf2 pathway in exacerbating Crizotinib-induced liver injury: implications for ferroptosis.

Guo L, Ma J, Xiao M, Liu J, Hu Z, Xia S, Li N, Yang Y, Gong H, Xi Y, Fu R, Jiang P, Xia C, Lauschke VM, Yan M. Guo L, et al. Among authors: lauschke vm. Cell Death Dis. 2024 Aug 19;15(8):600. doi: 10.1038/s41419-024-06993-z. Cell Death Dis. 2024. PMID: 39160159 Free PMC article.

8

Comparison of drug-induced liver injury risk between propylthiouracil and methimazole: A quantitative systems toxicology approach.

He Q, Li M, Ji P, Zheng A, Yao L, Zhu X, Shin JG, Lauschke VM, Han B, Xiang X. He Q, et al. Among authors: lauschke vm. Toxicol Appl Pharmacol. 2024 Oct;491:117064. doi: 10.1016/j.taap.2024.117064. Epub 2024 Aug 8. Toxicol Appl Pharmacol. 2024. PMID: 39122118

9

OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.

Mickols E, Meyer A, Handin N, Stüwe M, Eriksson J, Rudfeldt J, Blom K, Fryknäs M, Sellin ME, Lauschke VM, Karlgren M, Artursson P. Mickols E, et al. Among authors: lauschke vm. Sci Rep. 2024 Jul 27;14(1):17334. doi: 10.1038/s41598-024-67192-6. Sci Rep. 2024. PMID: 39068198 Free PMC article.

10

Population-scale variability of the human UDP-glycosyltransferase gene family.

González-Padilla D, Camara MD, Lauschke VM, Zhou Y. González-Padilla D, et al. Among authors: lauschke vm. J Genet Genomics. 2024 Nov;51(11):1228-1236. doi: 10.1016/j.jgg.2024.06.018. Epub 2024 Jul 4. J Genet Genomics. 2024. PMID: 38969258 Free article.

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