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A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia.
Sri S, Greenstein A, Granata A, Collcutt A, Jochems ACC, McColl BW, Castro BD, Webber C, Reyes CA, Hall C, Lawrence CB, Hawkes C, Pegasiou-Davies CM, Gibson C, Crawford CL, Smith C, Vivien D, McLean FH, Wiseman F, Brezzo G, Lalli G, Pritchard HAT, Markus HS, Bravo-Ferrer I, Taylor J, Leiper J, Berwick J, Gan J, Gallacher J, Moss J, Goense J, McMullan L, Work L, Evans L, Stringer MS, Ashford M, Abulfadl M, Conlon N, Malhotra P, Bath P, Canter R, Brown R, Ince S, Anderle S, Young S, Quick S, Szymkowiak S, Hill S, Allan S, Wang T, Quinn T, Procter T, Farr TD, Zhao X, Yang Z, Hainsworth AH, Wardlaw JM. Sri S, et al. Cereb Circ Cogn Behav. 2023 Oct 11;5:100189. doi: 10.1016/j.cccb.2023.100189. eCollection 2023. Cereb Circ Cogn Behav. 2023. PMID: 37941765 Free PMC article. Review.
Uncoupling of Ca2+ sparks from BK channels in cerebral arteries underlies hypoperfusion in hypertension-induced vascular dementia.
Taylor JL, Walsh KR, Mosneag IE, Danby TGE, Luka N, Chanda B, Schiessl I, Dunne RA, Hill-Eubanks D, Hennig GW, Allan SM, Nelson MT, Greenstein AS, Pritchard HAT. Taylor JL, et al. Among authors: greenstein as. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2307513120. doi: 10.1073/pnas.2307513120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549299 Free PMC article.
Don't forget to check your blood pressure.
Greenstein AS. Greenstein AS. J Hypertens. 2024 Sep 1;42(9):1528. doi: 10.1097/HJH.0000000000003797. Epub 2024 Aug 1. J Hypertens. 2024. PMID: 39088764 No abstract available.
Is it time to recommend cardiovascular protection for all?
Greenstein AS, Reusch JEB, Heagerty AM. Greenstein AS, et al. J Hypertens. 2024 Feb 1;42(2):224-226. doi: 10.1097/HJH.0000000000003501. Epub 2024 Jan 4. J Hypertens. 2024. PMID: 38165051 No abstract available.
Functionally linked potassium channel activity in cerebral endothelial and smooth muscle cells is compromised in Alzheimer's disease.
Taylor JL, Pritchard HAT, Walsh KR, Strangward P, White C, Hill-Eubanks D, Alakrawi M, Hennig GW, Allan SM, Nelson MT, Greenstein AS. Taylor JL, et al. Among authors: greenstein as. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2204581119. doi: 10.1073/pnas.2204581119. Epub 2022 Jun 21. Proc Natl Acad Sci U S A. 2022. PMID: 35727988 Free PMC article.
Perspectives on Cognitive Phenotypes and Models of Vascular Disease.
Muratoglu SC, Charette MF, Galis ZS, Greenstein AS, Daugherty A, Joutel A, Kozel BA, Wilcock DM, Collins EC, Sorond FA, Howell GR, Hyacinth HI, Lloyd KKC, Stenmark KR, Boehm M, Kahn ML, Corriveau R, Wells S, Bussey TJ, Sukoff Rizzo SJ, Iruela-Arispe ML. Muratoglu SC, et al. Among authors: greenstein as. Arterioscler Thromb Vasc Biol. 2022 Jul;42(7):831-838. doi: 10.1161/ATVBAHA.122.317395. Epub 2022 May 5. Arterioscler Thromb Vasc Biol. 2022. PMID: 35510549 Free PMC article. Review.
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