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DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer.
Momeny M, Tienhaara M, Sharma M, Chakroborty D, Varjus R, Takala I, Merisaari J, Padzik A, Vogt A, Paatero I, Elenius K, Laajala TD, Kurppa KJ, Westermarck J. Momeny M, et al. Among authors: paatero i. EMBO Mol Med. 2024 Jul;16(7):1603-1629. doi: 10.1038/s44321-024-00088-0. Epub 2024 Jun 17. EMBO Mol Med. 2024. PMID: 38886591 Free PMC article.
Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation.
Pekkonen P, Alve S, Balistreri G, Gramolelli S, Tatti-Bugaeva O, Paatero I, Niiranen O, Tuohinto K, Perälä N, Taiwo A, Zinovkina N, Repo P, Icay K, Ivaska J, Saharinen P, Hautaniemi S, Lehti K, Ojala PM. Pekkonen P, et al. Among authors: paatero i. Elife. 2018 May 1;7:e32490. doi: 10.7554/eLife.32490. Elife. 2018. PMID: 29712618 Free PMC article.
Intra- and extracellular signaling by endothelial neuregulin-1.
Iivanainen E, Paatero I, Heikkinen SM, Junttila TT, Cao R, Klint P, Jaakkola PM, Cao Y, Elenius K. Iivanainen E, et al. Among authors: paatero i. Exp Cell Res. 2007 Aug 1;313(13):2896-909. doi: 10.1016/j.yexcr.2007.03.042. Epub 2007 Apr 18. Exp Cell Res. 2007. PMID: 17499242
ErbB4 and its isoforms: patentable drug targets?
Paatero I, Elenius K. Paatero I, et al. Recent Pat DNA Gene Seq. 2008;2(1):27-33. doi: 10.2174/187221508783406602. Recent Pat DNA Gene Seq. 2008. PMID: 19075942 Review.
Interaction with ErbB4 promotes hypoxia-inducible factor-1α signaling.
Paatero I, Jokilammi A, Heikkinen PT, Iljin K, Kallioniemi OP, Jones FE, Jaakkola PM, Elenius K. Paatero I, et al. J Biol Chem. 2012 Mar 23;287(13):9659-9671. doi: 10.1074/jbc.M111.299537. Epub 2012 Feb 3. J Biol Chem. 2012. PMID: 22308027 Free PMC article.
43 results