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Page 1
Novel Mouse Model of Myocardial Infarction, Plaque Rupture, and Stroke Shows Improved Survival With Myeloperoxidase Inhibition.
Shamsuzzaman S, Deaton RA, Salamon A, Doviak H, Serbulea V, Milosek VM, Evans MA, Karnewar S, Saibaba S, Alencar GF, Shankman LS, Walsh K, Bekiranov S, Kocher O, Krieger M, Kull B, Persson M, Michaëlsson E, Bergenhem N, Heydarkhan-Hagvall S, Owens GK. Shamsuzzaman S, et al. Among authors: alencar gf. Circulation. 2024 Aug 27;150(9):687-705. doi: 10.1161/CIRCULATIONAHA.123.067931. Epub 2024 Jun 17. Circulation. 2024. PMID: 38881440 Free article.
Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
Alencar GF, Owsiany KM, Karnewar S, Sukhavasi K, Mocci G, Nguyen AT, Williams CM, Shamsuzzaman S, Mokry M, Henderson CA, Haskins R, Baylis RA, Finn AV, McNamara CA, Zunder ER, Venkata V, Pasterkamp G, Björkegren J, Bekiranov S, Owens GK. Alencar GF, et al. Circulation. 2020 Nov 24;142(21):2045-2059. doi: 10.1161/CIRCULATIONAHA.120.046672. Epub 2020 Jul 17. Circulation. 2020. PMID: 32674599 Free PMC article.
Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms.
Newman AAC, Serbulea V, Baylis RA, Shankman LS, Bradley X, Alencar GF, Owsiany K, Deaton RA, Karnewar S, Shamsuzzaman S, Salamon A, Reddy MS, Guo L, Finn A, Virmani R, Cherepanova OA, Owens GK. Newman AAC, et al. Among authors: alencar gf. Nat Metab. 2021 Feb;3(2):166-181. doi: 10.1038/s42255-020-00338-8. Epub 2021 Feb 22. Nat Metab. 2021. PMID: 33619382 Free PMC article.
IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering.
Karnewar S, Karnewar V, Deaton R, Shankman LS, Benavente ED, Williams CM, Bradley X, Alencar GF, Bulut GB, Kirmani S, Baylis RA, Zunder ER, den Ruijter HM, Pasterkamp G, Owens GK. Karnewar S, et al. Among authors: alencar gf. bioRxiv [Preprint]. 2023 Oct 14:2023.10.13.562255. doi: 10.1101/2023.10.13.562255. bioRxiv. 2023. Update in: Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1379-1392. doi: 10.1161/ATVBAHA.124.320800 PMID: 37873280 Free PMC article. Updated. Preprint.
IL-1β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice.
Karnewar S, Karnewar V, Deaton RA, Shankman LS, Benavente ED, Williams CM, Bradley X, Alencar GF, Bulut GB, Kirmani S, Baylis RA, Zunder ER, den Ruijter HM, Pasterkamp G, Owens GK. Karnewar S, et al. Among authors: alencar gf. Arterioscler Thromb Vasc Biol. 2024 Jun;44(6):1379-1392. doi: 10.1161/ATVBAHA.124.320800. Epub 2024 May 2. Arterioscler Thromb Vasc Biol. 2024. PMID: 38695167
Revealing the Origins of Foam Cells in Atherosclerotic Lesions.
Owsiany KM, Alencar GF, Owens GK. Owsiany KM, et al. Among authors: alencar gf. Arterioscler Thromb Vasc Biol. 2019 May;39(5):836-838. doi: 10.1161/ATVBAHA.119.312557. Arterioscler Thromb Vasc Biol. 2019. PMID: 31017823 Free PMC article. No abstract available.
Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective.
Cherepanova OA, Gomez D, Shankman LS, Swiatlowska P, Williams J, Sarmento OF, Alencar GF, Hess DL, Bevard MH, Greene ES, Murgai M, Turner SD, Geng YJ, Bekiranov S, Connelly JJ, Tomilin A, Owens GK. Cherepanova OA, et al. Among authors: alencar gf. Nat Med. 2016 Jun;22(6):657-65. doi: 10.1038/nm.4109. Epub 2016 May 16. Nat Med. 2016. PMID: 27183216 Free PMC article.
Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells.
Aherrahrou R, Guo L, Nagraj VP, Aguhob A, Hinkle J, Chen L, Yuhl Soh J, Lue D, Alencar GF, Boltjes A, van der Laan SW, Farber E, Fuller D, Anane-Wae R, Akingbesote N, Manichaikul AW, Ma L, Kaikkonen MU, Björkegren JLM, Önengüt-Gümüşcü S, Pasterkamp G, Miller CL, Owens GK, Finn A, Navab M, Fogelman AM, Berliner JA, Civelek M. Aherrahrou R, et al. Among authors: alencar gf. Circ Res. 2020 Dec 4;127(12):1552-1565. doi: 10.1161/CIRCRESAHA.120.317415. Epub 2020 Oct 12. Circ Res. 2020. PMID: 33040646 Free PMC article.
KLF4 (Kruppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue inflammation.
Bulut GB, Alencar GF, Owsiany KM, Nguyen AT, Karnewar S, Haskins RM, Waller LK, Cherepanova OA, Deaton RA, Shankman LS, Keller SR, Owens GK. Bulut GB, et al. Among authors: alencar gf. Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):284-301. doi: 10.1161/ATVBAHA.120.314703. Epub 2020 Oct 15. Arterioscler Thromb Vasc Biol. 2021. PMID: 33054397 Free PMC article.
18 results