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Extending the Time Window for Tenecteplase by Effective Reperfusion of Penumbral Tissue in Patients with Large Vessel Occlusion (ETERNAL-LVO): Rationale and design of a multicenter, prospective, randomized, open-label, blinded-endpoint, controlled phase 3 trial.
Yogendrakumar V, Campbell B, Churilov L, Garcia-Esperon C, Choi P, Cordato D, Guha P, Sharma G, Chen C, McDonald A, Thijs V, Mamun A, Dos Santos A, Balabanski AH, Kleinig T, Butcher K, Devlin M, O'Rourke F, Donnan G, Davis SM, Levi C, Ma H, Parsons M. Yogendrakumar V, et al. Among authors: garcia esperon c. Int J Stroke. 2024 Dec 9:17474930241308660. doi: 10.1177/17474930241308660. Online ahead of print. Int J Stroke. 2024. PMID: 39654273
Intravenous glibenclamide for cerebral oedema after large hemispheric stroke (CHARM): a phase 3, double-blind, placebo-controlled, randomised trial.
Sheth KN, Albers GW, Saver JL, Campbell BCV, Molyneaux BJ, Hinson HE, Cordonnier C, Steiner T, Toyoda K, Wintermark M, Littauer R, Collins J, Lucas N, Nogueira RG, Simard JM, Wald M, Dawson K, Kimberly WT; CHARM Trial investigators. Sheth KN, et al. Lancet Neurol. 2024 Dec;23(12):1205-1213. doi: 10.1016/S1474-4422(24)00425-3. Lancet Neurol. 2024. PMID: 39577921 Clinical Trial.
Development and Validation of a Clinical Score to Predict Epilepsy After Cerebral Venous Thrombosis.
Lindgren E, Shu L, Simaan N, Krzywicka K, de Winter MA, Sánchez van Kammen M, Molad J, Klein P, Hallevi H, Barnea R, Heldner MR, Hiltunen S, de Sousa DA, Ferro JM, Arauz A, Putaala J, Arnold M, Nguyen TN, Stretz C, Tatlisumak T, Jood K, Yaghi S, Leker RR, Coutinho JM; DIAS research collaboration; Mansour M, Canhão P, Ekizoglu E, Rodrigues M, Silva EM, Garcia-Esperon C, Arnao V, Aladin S, Mendel R, Aridon P, Sezgin M, Alasheev A, Smolkin A, Guisado-Alonso D, Yesilot N, Barboza MA, Ghiasian M, Silvis SM, Fang T, Siegler JE, Wu T, Wilson D, Asad SD, Al Kasab S, Almallouhi E, Frontera J, Rothstein A, Bakradze E, Omran SS, Henninger N, Kuohn L, Zubair A, Sharma R, Kerrigan D, Aziz Y, Mistry E, Zuurbier SM. Lindgren E, et al. Among authors: garcia esperon c. JAMA Neurol. 2024 Dec 1;81(12):1274-1283. doi: 10.1001/jamaneurol.2024.3481. JAMA Neurol. 2024. PMID: 39432281
Exploring ischemic core growth rate and endovascular therapy benefit in large core patients.
Lin L, Wang Y, Chen C, Bivard A, Butcher K, Garcia-Esperon C, Spratt NJ, Levi CR, Cheng X, Dong Q, Parsons MW; INSPIRE study group. Lin L, et al. Among authors: garcia esperon c. J Cereb Blood Flow Metab. 2024 Dec;44(12):1593-1604. doi: 10.1177/0271678X241242911. Epub 2024 Jul 26. J Cereb Blood Flow Metab. 2024. PMID: 39054948 Free PMC article.
Tenecteplase versus alteplase for thrombolysis in patients selected by use of perfusion imaging within 4·5 h of onset of ischaemic stroke (TASTE): a multicentre, randomised, controlled, phase 3 non-inferiority trial.
Parsons MW, Yogendrakumar V, Churilov L, Garcia-Esperon C, Campbell BCV, Russell ML, Sharma G, Chen C, Lin L, Chew BL, Ng FC, Deepak A, Choi PMC, Kleinig TJ, Cordato DJ, Wu TY, Fink JN, Ma H, Phan TG, Markus HS, Molina CA, Tsai CH, Lee JT, Jeng JS, Strbian D, Meretoja A, Arenillas JF, Buck BH, Devlin MJ, Brown H, Butcher KS, O'Brien B, Sabet A, Wijeratne T, Bivard A, Grimley RS, Agarwal S, Munshi SK, Donnan GA, Davis SM, Miteff F, Spratt NJ, Levi CR; TASTE investigators. Parsons MW, et al. Among authors: garcia esperon c. Lancet Neurol. 2024 Aug;23(8):775-786. doi: 10.1016/S1474-4422(24)00206-0. Epub 2024 Jun 13. Lancet Neurol. 2024. PMID: 38880118 Clinical Trial.
Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial.
Coutts SB, Ankolekar S, Appireddy R, Arenillas JF, Assis Z, Bailey P, Barber PA, Bazan R, Buck BH, Butcher KS, Camden MC, Campbell BCV, Casaubon LK, Catanese L, Chatterjee K, Choi PMC, Clarke B, Dowlatshahi D, Ferrari J, Field TS, Ganesh A, Ghia D, Goyal M, Greisenegger S, Halse O, Horn M, Hunter G, Imoukhuede O, Kelly PJ, Kennedy J, Kenney C, Kleinig TJ, Krishnan K, Lima F, Mandzia JL, Marko M, Martins SO, Medvedev G, Menon BK, Mishra SM, Molina C, Moussaddy A, Muir KW, Parsons MW, Penn AMW, Pille A, Pontes-Neto OM, Roffe C, Serena J, Simister R, Singh N, Spratt N, Strbian D, Tham CH, Wiggam MI, Williams DJ, Willmot MR, Wu T, Yu AYX, Zachariah G, Zafar A, Zerna C, Hill MD; TEMPO-2 investigators. Coutts SB, et al. Lancet. 2024 Jun 15;403(10444):2597-2605. doi: 10.1016/S0140-6736(24)00921-8. Epub 2024 May 17. Lancet. 2024. PMID: 38768626 Clinical Trial.
96 results