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Page 1
Genetic and environmental interactions contribute to immune variation in rewilded mice.
Oyesola O, Downie AE, Howard N, Barre RS, Kiwanuka K, Zaldana K, Chen YH, Menezes A, Lee SC, Devlin J, Mondragón-Palomino O, Souza COS, Herrmann C, Koralov SB, Cadwell K, Graham AL, Loke P. Oyesola O, et al. Among authors: loke p. Nat Immunol. 2024 Jul;25(7):1270-1282. doi: 10.1038/s41590-024-01862-5. Epub 2024 Jun 14. Nat Immunol. 2024. PMID: 38877178 Free PMC article.
Helminth infection promotes colonization resistance via type 2 immunity.
Ramanan D, Bowcutt R, Lee SC, Tang MS, Kurtz ZD, Ding Y, Honda K, Gause WC, Blaser MJ, Bonneau RA, Lim YA, Loke P, Cadwell K. Ramanan D, et al. Among authors: loke p. Science. 2016 Apr 29;352(6285):608-12. doi: 10.1126/science.aaf3229. Epub 2016 Apr 14. Science. 2016. PMID: 27080105 Free PMC article.
Rapid environmental effects on gut nematode susceptibility in rewilded mice.
Leung JM, Budischak SA, Chung The H, Hansen C, Bowcutt R, Neill R, Shellman M, Loke P, Graham AL. Leung JM, et al. Among authors: loke p. PLoS Biol. 2018 Mar 8;16(3):e2004108. doi: 10.1371/journal.pbio.2004108. eCollection 2018 Mar. PLoS Biol. 2018. PMID: 29518091 Free PMC article.
Getting a Taste for Parasites in the Gut.
Loke P, Cadwell K. Loke P, et al. Immunity. 2018 Jul 17;49(1):16-18. doi: 10.1016/j.immuni.2018.07.002. Immunity. 2018. PMID: 30021142 Free article.
Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice.
Lubkin A, Lee WL, Alonzo F 3rd, Wang C, Aligo J, Keller M, Girgis NM, Reyes-Robles T, Chan R, O'Malley A, Buckley P, Vozhilla N, Vasquez MT, Su J, Sugiyama M, Yeung ST, Coffre M, Bajwa S, Chen E, Martin P, Kim SY, Loomis C, Worthen GS, Shopsin B, Khanna KM, Weinstock D, Lynch AS, Koralov SB, Loke P, Cadwell K, Torres VJ. Lubkin A, et al. Among authors: loke p. Cell Host Microbe. 2019 Mar 13;25(3):463-470.e9. doi: 10.1016/j.chom.2019.01.015. Epub 2019 Feb 21. Cell Host Microbe. 2019. PMID: 30799265 Free PMC article.
IFN-I and IL-22 mediate protective effects of intestinal viral infection.
Neil JA, Matsuzawa-Ishimoto Y, Kernbauer-Hölzl E, Schuster SL, Sota S, Venzon M, Dallari S, Galvao Neto A, Hine A, Hudesman D, Loke P, Nice TJ, Cadwell K. Neil JA, et al. Among authors: loke p. Nat Microbiol. 2019 Oct;4(10):1737-1749. doi: 10.1038/s41564-019-0470-1. Epub 2019 Jun 10. Nat Microbiol. 2019. PMID: 31182797 Free PMC article.
Rewilding Nod2 and Atg16l1 Mutant Mice Uncovers Genetic and Environmental Contributions to Microbial Responses and Immune Cell Composition.
Lin JD, Devlin JC, Yeung F, McCauley C, Leung JM, Chen YH, Cronkite A, Hansen C, Drake-Dunn C, Ruggles KV, Cadwell K, Graham AL, Loke P. Lin JD, et al. Among authors: loke p. Cell Host Microbe. 2020 May 13;27(5):830-840.e4. doi: 10.1016/j.chom.2020.03.001. Epub 2020 Mar 24. Cell Host Microbe. 2020. PMID: 32209431 Free PMC article.
Altered Immunity of Laboratory Mice in the Natural Environment Is Associated with Fungal Colonization.
Yeung F, Chen YH, Lin JD, Leung JM, McCauley C, Devlin JC, Hansen C, Cronkite A, Stephens Z, Drake-Dunn C, Fulmer Y, Shopsin B, Ruggles KV, Round JL, Loke P, Graham AL, Cadwell K. Yeung F, et al. Among authors: loke p. Cell Host Microbe. 2020 May 13;27(5):809-822.e6. doi: 10.1016/j.chom.2020.02.015. Epub 2020 Mar 24. Cell Host Microbe. 2020. PMID: 32209432 Free PMC article.
An intestinal organoid-based platform that recreates susceptibility to T-cell-mediated tissue injury.
Matsuzawa-Ishimoto Y, Hine A, Shono Y, Rudensky E, Lazrak A, Yeung F, Neil JA, Yao X, Chen YH, Heaney T, Schuster SL, Zwack EE, Axelrad JE, Hudesman D, Tsai JJ, Nichols K, Dewan MZ, Cammer M, Beal A, Hoffman S, Geddes B, Bertin J, Liu C, Torres VJ, Loke P, van den Brink MRM, Cadwell K. Matsuzawa-Ishimoto Y, et al. Among authors: loke p. Blood. 2020 Jun 25;135(26):2388-2401. doi: 10.1182/blood.2019004116. Blood. 2020. PMID: 32232483 Free PMC article.
179 results