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Page 1
Mechanistic patterns and clinical implications of oncogenic tyrosine kinase fusions in human cancers.
Chiarle R, Cheong TC, Jang A, Wang Q, Leonardi G, Ricciuti B, Alessi J, Federico AD, Awad M, Lehtinen M, Harris M. Chiarle R, et al. Among authors: cheong tc. Res Sq [Preprint]. 2024 Jan 17:rs.3.rs-3782958. doi: 10.21203/rs.3.rs-3782958/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Jun 14;15(1):5110. doi: 10.1038/s41467-024-49499-0. PMID: 38313284 Free PMC article. Updated. Preprint.
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Compagno M, Wang Q, Pighi C, Cheong TC, Meng FL, Poggio T, Yeap LS, Karaca E, Blasco RB, Langellotto F, Ambrogio C, Voena C, Wiestner A, Kasar SN, Brown JR, Sun J, Wu CJ, Gostissa M, Alt FW, Chiarle R. Compagno M, et al. Among authors: cheong tc. Nature. 2017 Feb 23;542(7642):489-493. doi: 10.1038/nature21406. Epub 2017 Feb 15. Nature. 2017. PMID: 28199309 Free PMC article.
Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma.
Menotti M, Ambrogio C, Cheong TC, Pighi C, Mota I, Cassel SH, Compagno M, Wang Q, Dall'Olio R, Minero VG, Poggio T, Sharma GG, Patrucco E, Mastini C, Choudhari R, Pich A, Zamo A, Piva R, Giliani S, Mologni L, Collings CK, Kadoch C, Gambacorti-Passerini C, Notarangelo LD, Anton IM, Voena C, Chiarle R. Menotti M, et al. Among authors: cheong tc. Nat Med. 2019 Jan;25(1):130-140. doi: 10.1038/s41591-018-0262-9. Epub 2018 Dec 3. Nat Med. 2019. PMID: 30510251 Free PMC article.
Tyrosine phosphatases regulate resistance to ALK inhibitors in ALK+ anaplastic large cell lymphoma.
Karaca Atabay E, Mecca C, Wang Q, Ambrogio C, Mota I, Prokoph N, Mura G, Martinengo C, Patrucco E, Leonardi G, Hossa J, Pich A, Mologni L, Gambacorti-Passerini C, Brugières L, Geoerger B, Turner SD, Voena C, Cheong TC, Chiarle R. Karaca Atabay E, et al. Among authors: cheong tc. Blood. 2022 Feb 3;139(5):717-731. doi: 10.1182/blood.2020008136. Blood. 2022. PMID: 34657149 Free PMC article.
ERα-associated translocations underlie oncogene amplifications in breast cancer.
Lee JJ, Jung YL, Cheong TC, Espejo Valle-Inclan J, Chu C, Gulhan DC, Ljungström V, Jin H, Viswanadham VV, Watson EV, Cortés-Ciriano I, Elledge SJ, Chiarle R, Pellman D, Park PJ. Lee JJ, et al. Among authors: cheong tc. Nature. 2023 Jun;618(7967):1024-1032. doi: 10.1038/s41586-023-06057-w. Epub 2023 May 17. Nature. 2023. PMID: 37198482 Free PMC article.
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.
Mota I, Patrucco E, Mastini C, Mahadevan NR, Thai TC, Bergaggio E, Cheong TC, Leonardi G, Karaca-Atabay E, Campisi M, Poggio T, Menotti M, Ambrogio C, Longo DL, Klaeger S, Keshishian H, Sztupinszki ZM, Szallasi Z, Keskin DB, Duke-Cohan JS, Reinhold B, Carr SA, Wu CJ, Moynihan KD, Irvine DJ, Barbie DA, Reinherz EL, Voena C, Awad MM, Blasco RB, Chiarle R. Mota I, et al. Among authors: cheong tc. Nat Cancer. 2023 Jul;4(7):1016-1035. doi: 10.1038/s43018-023-00591-2. Epub 2023 Jul 10. Nat Cancer. 2023. PMID: 37430060
25 results