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Page 1
Fibrolytic vaccination against ADAM12 reduces desmoplasia in preclinical pancreatic adenocarcinomas.
Chen J, Sobecki M, Krzywinska E, Thierry K, Masmoudi M, Nagarajan S, Fan Z, He J, Ferapontova I, Nelius E, Seehusen F, Gotthardt D, Takeda N, Sommer L, Sexl V, Münz C, DeNardo D, Hennino A, Stockmann C. Chen J, et al. Among authors: nelius e. EMBO Mol Med. 2024 Dec;16(12):3033-3056. doi: 10.1038/s44321-024-00157-4. Epub 2024 Oct 30. EMBO Mol Med. 2024. PMID: 39478152 Free PMC article.
Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure.
Fan Z, Karakone M, Nagarajan S, Nagy N, Mildenberger W, Petrova E, Hinte LC, Bijnen M, Häne P, Nelius E, Chen J, Ferapontova I, von Meyenn F, Trepiccione F, Berber M, Ribas DP, Eichmann A, Zennaro MC, Takeda N, Fischer JW, Spyroglou A, Reincke M, Beuschlein F, Loffing J, Greter M, Stockmann C. Fan Z, et al. Among authors: nelius e. Cell Rep. 2024 Jul 23;43(7):114395. doi: 10.1016/j.celrep.2024.114395. Epub 2024 Jun 26. Cell Rep. 2024. PMID: 38941187 Free article.
Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF-1α.
Pelletier A, Nelius E, Fan Z, Khatchatourova E, Alvarado-Diaz A, He J, Krzywinska E, Sobecki M, Nagarajan S, Kerdiles Y, Fandrey J, Gotthardt D, Sexl V, de Bock K, Stockmann C. Pelletier A, et al. Among authors: nelius e. EMBO Rep. 2023 Jun 5;24(6):e56156. doi: 10.15252/embr.202256156. Epub 2023 Mar 29. EMBO Rep. 2023. PMID: 36987917 Free PMC article.
Vaccination-based immunotherapy to target profibrotic cells in liver and lung.
Sobecki M, Chen J, Krzywinska E, Nagarajan S, Fan Z, Nelius E, Monné Rodriguez JM, Seehusen F, Hussein A, Moschini G, Hajam EY, Kiran R, Gotthardt D, Debbache J, Badoual C, Sato T, Isagawa T, Takeda N, Tanchot C, Tartour E, Weber A, Werner S, Loffing J, Sommer L, Sexl V, Münz C, Feghali-Bostwick C, Pachera E, Distler O, Snedeker J, Jamora C, Stockmann C. Sobecki M, et al. Among authors: nelius e. Cell Stem Cell. 2022 Oct 6;29(10):1459-1474.e9. doi: 10.1016/j.stem.2022.08.012. Epub 2022 Sep 15. Cell Stem Cell. 2022. PMID: 36113462 Free article.