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Page 1
Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis.
Engesser J, Khatri R, Schaub DP, Zhao Y, Paust HJ, Sultana Z, Asada N, Riedel JH, Sivayoganathan V, Peters A, Kaffke A, Jauch-Speer SL, Goldbeck-Strieder T, Puelles VG, Wenzel UO, Steinmetz OM, Hoxha E, Turner JE, Mittrücker HW, Wiech T, Huber TB, Bonn S, Krebs CF, Panzer U. Engesser J, et al. Among authors: jauch speer sl. Nat Commun. 2024 Sep 19;15(1):8220. doi: 10.1038/s41467-024-52525-w. Nat Commun. 2024. PMID: 39300109 Free PMC article.
Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening.
Enk LUB, Hellmig M, Riecken K, Kilian C, Datlinger P, Jauch-Speer SL, Neben T, Sultana Z, Sivayoganathan V, Borchers A, Paust HJ, Zhao Y, Asada N, Liu S, Agalioti T, Pelczar P, Wiech T, Bock C, Huber TB, Huber S, Bonn S, Gagliani N, Fehse B, Panzer U, Krebs CF. Enk LUB, et al. Among authors: jauch speer sl. Sci Immunol. 2024 Jun 14;9(96):eadd6774. doi: 10.1126/sciimmunol.add6774. Epub 2024 Jun 14. Sci Immunol. 2024. PMID: 38875317
The CCR6/CCL20 axis expands RORγt+ Tregs to protect from glomerulonephritis.
Herrnstadt GR, Niehus CB, Ramcke T, Hagenstein J, Ehnold LI, Nosko A, Warkotsch MT, Feindt FC, Melderis S, Paust HJ, Sivayoganathan V, Jauch-Speer SL, Wong MN, Indenbirken D, Krebs CF, Huber TB, Panzer U, Puelles VG, Kluger MA, Steinmetz OM. Herrnstadt GR, et al. Among authors: jauch speer sl. Kidney Int. 2023 Jul;104(1):74-89. doi: 10.1016/j.kint.2023.02.027. Epub 2023 Mar 15. Kidney Int. 2023. PMID: 36924892
Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever.
Jorch SK, McNally A, Berger P, Wolf J, Kaiser K, Chetrusca Covash A, Robeck S, Pastau I, Fehler O, Jauch-Speer SL, Hermann S, Schäfers M, Van Gorp H, Kanneganti A, Dehoorne J, Haerynck F, Penco F, Gattorno M, Chae JJ, Kubes P, Lamkanfi M, Wullaert A, Sperandio M, Vogl T, Roth J, Austermann J. Jorch SK, et al. Among authors: jauch speer sl. J Allergy Clin Immunol. 2023 Jul;152(1):230-243. doi: 10.1016/j.jaci.2023.01.037. Epub 2023 Feb 22. J Allergy Clin Immunol. 2023. PMID: 36822481 Free article.