Suga H - Search Results

1

PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination.

Franzolin G, Brundu S, Cojocaru CF, Curatolo A, Ponzo M, Mastrantonio R, Mihara E, Kumanogoh A, Suga H, Takagi J, Tamagnone L, Giraudo E. Franzolin G, et al. Among authors: suga h. Cancer Immunol Res. 2024 Sep 3;12(9):1286-1301. doi: 10.1158/2326-6066.CIR-23-0289. Cancer Immunol Res. 2024. PMID: 38874583 Free PMC article.

2

Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide.

Matsunaga Y, Bashiruddin NK, Kitago Y, Takagi J, Suga H. Matsunaga Y, et al. Among authors: suga h. Cell Chem Biol. 2016 Nov 17;23(11):1341-1350. doi: 10.1016/j.chembiol.2016.09.015. Epub 2016 Oct 27. Cell Chem Biol. 2016. PMID: 27984026 Free article.

3

Facile Synthesis of Dimeric Thioether-Macrocyclic Peptides with Antibody-like Affinity against Plexin-B1.

Bashiruddin NK, Matsunaga Y, Nagano M, Takagi J, Suga H. Bashiruddin NK, et al. Among authors: suga h. Bioconjug Chem. 2018 Jun 20;29(6):1847-1851. doi: 10.1021/acs.bioconjchem.8b00219. Epub 2018 May 21. Bioconjug Chem. 2018. PMID: 29714478

4

Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation.

Bashiruddin NK, Hayashi M, Nagano M, Wu Y, Matsunaga Y, Takagi J, Nakashima T, Suga H. Bashiruddin NK, et al. Among authors: suga h. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31070-31077. doi: 10.1073/pnas.2012266117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229551 Free PMC article.

5

Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins.

Mihara E, Watanabe S, Bashiruddin NK, Nakamura N, Matoba K, Sano Y, Maini R, Yin Y, Sakai K, Arimori T, Matsumoto K, Suga H, Takagi J. Mihara E, et al. Among authors: suga h. Nat Commun. 2021 Mar 9;12(1):1543. doi: 10.1038/s41467-021-21875-0. Nat Commun. 2021. PMID: 33750839 Free PMC article.

6

Macrocyclic peptides that inhibit Wnt signalling via interaction with Wnt3a.

Otero-Ramirez ME, Matoba K, Mihara E, Passioura T, Takagi J, Suga H. Otero-Ramirez ME, et al. Among authors: suga h. RSC Chem Biol. 2020 Mar 24;1(1):26-34. doi: 10.1039/d0cb00016g. eCollection 2020 Apr 16. RSC Chem Biol. 2020. PMID: 34458746 Free PMC article.

7

De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist.

Komatsu Y, Terasaka N, Sakai K, Mihara E, Wakabayashi R, Matsumoto K, Hilvert D, Takagi J, Suga H. Komatsu Y, et al. Among authors: suga h. iScience. 2021 Oct 16;24(11):103302. doi: 10.1016/j.isci.2021.103302. eCollection 2021 Nov 19. iScience. 2021. PMID: 34805784 Free PMC article.

8

De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function.

Sugano-Nakamura N, Matoba K, Hirose M, Bashiruddin NK, Matsunaga Y, Yamashita K, Hirata K, Yamamoto M, Arimori T, Suga H, Takagi J. Sugano-Nakamura N, et al. Among authors: suga h. Structure. 2022 Oct 6;30(10):1411-1423.e4. doi: 10.1016/j.str.2022.07.008. Epub 2022 Aug 17. Structure. 2022. PMID: 35981535 Free article.

9

Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions.

Sakai K, Sugano-Nakamura N, Mihara E, Rojas-Chaverra NM, Watanabe S, Sato H, Imamura R, Voon DC, Sakai I, Yamasaki C, Tateno C, Shibata M, Suga H, Takagi J, Matsumoto K. Sakai K, et al. Among authors: suga h. Nat Biomed Eng. 2023 Feb;7(2):164-176. doi: 10.1038/s41551-022-00955-6. Epub 2022 Nov 7. Nat Biomed Eng. 2023. PMID: 36344661 Free PMC article.

10

Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist.

Miao W, Sakai K, Ozawa N, Nishiuchi T, Suzuki Y, Ito K, Morioka T, Umitsu M, Takagi J, Suga H, Matsumoto K. Miao W, et al. Among authors: suga h. Sci Rep. 2018 Nov 7;8(1):16492. doi: 10.1038/s41598-018-34835-4. Sci Rep. 2018. PMID: 30405161 Free PMC article.

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