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The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche.
Gonzalez-Sanchez E, Vaquero J, Caballero-Diaz D, Grzelak J, Fusté NP, Bertran E, Amengual J, Garcia-Saez J, Martín-Mur B, Gut M, Esteve-Codina A, Alay A, Coulouarn C, Calero-Perez S, Valdecantos P, Valverde AM, Sánchez A, Herrera B, Fabregat I. Gonzalez-Sanchez E, et al. Among authors: vaquero j. J Pathol. 2024 Aug;263(4-5):482-495. doi: 10.1002/path.6299. Epub 2024 Jun 14. J Pathol. 2024. PMID: 38872438
E-cadherin, guardian of liver physiology.
Gonzalez-Sanchez E, Vaquero J, Fouassier L, Chignard N. Gonzalez-Sanchez E, et al. Among authors: vaquero j. Clin Res Hepatol Gastroenterol. 2015 Feb;39(1):3-6. doi: 10.1016/j.clinre.2014.09.008. Epub 2014 Nov 12. Clin Res Hepatol Gastroenterol. 2015. PMID: 25459993
Cholangiopathy aggravation is caused by VDR ablation and alleviated by VDR-independent vitamin D signaling in ABCB4 knockout mice.
Gonzalez-Sanchez E, El Mourabit H, Jager M, Clavel M, Moog S, Vaquero J, Ledent T, Cadoret A, Gautheron J, Fouassier L, Wendum D, Chignard N, Housset C. Gonzalez-Sanchez E, et al. Among authors: vaquero j. Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166067. doi: 10.1016/j.bbadis.2020.166067. Epub 2021 Jan 6. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33418034 Free article.
The TGF-β Pathway: A Pharmacological Target in Hepatocellular Carcinoma?
Gonzalez-Sanchez E, Vaquero J, Férnandez-Barrena MG, Lasarte JJ, Avila MA, Sarobe P, Reig M, Calvo M, Fabregat I. Gonzalez-Sanchez E, et al. Among authors: vaquero j. Cancers (Basel). 2021 Jun 29;13(13):3248. doi: 10.3390/cancers13133248. Cancers (Basel). 2021. PMID: 34209646 Free PMC article. Review.
Zinc Finger E-Box Binding Homeobox 1 Promotes Cholangiocarcinoma Progression Through Tumor Dedifferentiation and Tumor-Stroma Paracrine Signaling.
Lobe C, Vallette M, Arbelaiz A, Gonzalez-Sanchez E, Izquierdo L, Pellat A, Guedj N, Louis C, Paradis V, Banales JM, Coulouarn C, Housset C, Vaquero J, Fouassier L. Lobe C, et al. Among authors: vaquero j. Hepatology. 2021 Dec;74(6):3194-3212. doi: 10.1002/hep.32069. Epub 2021 Sep 28. Hepatology. 2021. PMID: 34297412 Free article.
Genetic alterations shaping tumor response to anti-EGFR therapies.
Vaquero J, Pavy A, Gonzalez-Sanchez E, Meredith M, Arbelaiz A, Fouassier L. Vaquero J, et al. Drug Resist Updat. 2022 Sep;64:100863. doi: 10.1016/j.drup.2022.100863. Epub 2022 Aug 27. Drug Resist Updat. 2022. PMID: 36063655 Review.
Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance.
Calvisi DF, Boulter L, Vaquero J, Saborowski A, Fabris L, Rodrigues PM, Coulouarn C, Castro RE, Segatto O, Raggi C, van der Laan LJW, Carpino G, Goeppert B, Roessler S, Kendall TJ, Evert M, Gonzalez-Sanchez E, Valle JW, Vogel A, Bridgewater J, Borad MJ, Gores GJ, Roberts LR, Marin JJG, Andersen JB, Alvaro D, Forner A, Banales JM, Cardinale V, Macias RIR, Vicent S, Chen X, Braconi C, Verstegen MMA, Fouassier L; CCA Model Consortium. Calvisi DF, et al. Among authors: vaquero j. Nat Rev Gastroenterol Hepatol. 2023 Jul;20(7):462-480. doi: 10.1038/s41575-022-00739-y. Epub 2023 Feb 8. Nat Rev Gastroenterol Hepatol. 2023. PMID: 36755084 Free article. Review.
694 results