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The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche.
Gonzalez-Sanchez E, Vaquero J, Caballero-Diaz D, Grzelak J, Fusté NP, Bertran E, Amengual J, Garcia-Saez J, Martín-Mur B, Gut M, Esteve-Codina A, Alay A, Coulouarn C, Calero-Perez S, Valdecantos P, Valverde AM, Sánchez A, Herrera B, Fabregat I. Gonzalez-Sanchez E, et al. Among authors: alay a. J Pathol. 2024 Aug;263(4-5):482-495. doi: 10.1002/path.6299. Epub 2024 Jun 14. J Pathol. 2024. PMID: 38872438
Clathrin switches transforming growth factor-β role to pro-tumorigenic in liver cancer.
Caballero-Díaz D, Bertran E, Peñuelas-Haro I, Moreno-Càceres J, Malfettone A, López-Luque J, Addante A, Herrera B, Sánchez A, Alay A, Solé X, Serrano T, Ramos E, Fabregat I. Caballero-Díaz D, et al. Among authors: alay a. J Hepatol. 2020 Jan;72(1):125-134. doi: 10.1016/j.jhep.2019.09.012. Epub 2019 Sep 25. J Hepatol. 2020. PMID: 31562907 Free article.
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression.
Peñuelas-Haro I, Espinosa-Sotelo R, Crosas-Molist E, Herranz-Itúrbide M, Caballero-Díaz D, Alay A, Solé X, Ramos E, Serrano T, Martínez-Chantar ML, Knaus UG, Cuezva JM, Zorzano A, Bertran E, Fabregat I. Peñuelas-Haro I, et al. Among authors: alay a. Hepatology. 2023 Aug 1;78(2):416-433. doi: 10.1002/hep.32702. Epub 2022 Sep 17. Hepatology. 2023. PMID: 35920301 Free PMC article.
Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma.
Espinosa-Sotelo R, Fusté NP, Peñuelas-Haro I, Alay A, Pons G, Almodóvar X, Albaladejo J, Sánchez-Vera I, Bonilla-Amadeo R, Dituri F, Serino G, Ramos E, Serrano T, Calvo M, Martínez-Chantar ML, Giannelli G, Bertran E, Fabregat I. Espinosa-Sotelo R, et al. Among authors: alay a. Redox Biol. 2023 Sep;65:102818. doi: 10.1016/j.redox.2023.102818. Epub 2023 Jul 13. Redox Biol. 2023. PMID: 37463530 Free PMC article.
Neoadjuvant sunitinib plus exemestane in post-menopausal women with hormone receptor-positive/HER2-negative early-stage breast cancer (SUT_EXE-08): a phase I/II trial.
Fullana B, Morales S, Petit A, Alay A, Verdaguer H, Climent F, Navarro-Perez V, Cejuela M, Galvan P, Gumà A, Llombart-Cussac A, Cordero D, Casanovas O, Prat A, Gil-Gil M, Pernas S. Fullana B, et al. Among authors: alay a. Sci Rep. 2024 Oct 9;14(1):23626. doi: 10.1038/s41598-024-72152-1. Sci Rep. 2024. PMID: 39384801 Free PMC article. Clinical Trial.
Transcriptional analysis of landmark molecular pathways in lung adenocarcinoma results in a clinically relevant classification with potential therapeutic implications.
Hijazo-Pechero S, Alay A, Cordero D, Marín R, Vilariño N, Palmero R, Brenes J, Montalban-Casafont A, Nadal E, Solé X. Hijazo-Pechero S, et al. Among authors: alay a. Mol Oncol. 2024 Feb;18(2):453-470. doi: 10.1002/1878-0261.13550. Epub 2023 Dec 21. Mol Oncol. 2024. PMID: 37943164 Free PMC article.
17 results