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Effect of substituents at the C3´, C3´N, C10 and C2-meta-benzoate positions of taxane derivatives on their activity against resistant cancer cells.
Daniel P, Balušíková K, Truksa J, Černý J, Jaček M, Jelínek M, Mulenga MJV, Voráčová K, Chen L, Wei L, Sun Y, Ojima I, Kovář J. Daniel P, et al. Among authors: wei l. Toxicol Appl Pharmacol. 2024 Aug;489:116993. doi: 10.1016/j.taap.2024.116993. Epub 2024 Jun 12. Toxicol Appl Pharmacol. 2024. PMID: 38870637
Substituents at the C3' and C3'N positions are critical for taxanes to overcome acquired resistance of cancer cells to paclitaxel.
Jelínek M, Balušíková K, Daniel P, Němcová-Fürstová V, Kirubakaran P, Jaček M, Wei L, Wang X, Vondrášek J, Ojima I, Kovář J. Jelínek M, et al. Among authors: wei l. Toxicol Appl Pharmacol. 2018 May 15;347:79-91. doi: 10.1016/j.taap.2018.04.002. Epub 2018 Apr 4. Toxicol Appl Pharmacol. 2018. PMID: 29625142 Free PMC article.
ABCB1 Amplicon Contains Cyclic AMP Response Element-Driven TRIP6 Gene in Taxane-Resistant MCF-7 Breast Cancer Sublines.
Daniel P, Balušíková K, Václavíková R, Šeborová K, Ransdorfová Š, Valeriánová M, Wei L, Jelínek M, Tlapáková T, Fleischer T, Kristensen VN, Souček P, Ojima I, Kovář J. Daniel P, et al. Among authors: wei l. Genes (Basel). 2023 Jan 23;14(2):296. doi: 10.3390/genes14020296. Genes (Basel). 2023. PMID: 36833223 Free PMC article.
SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins.
Yan S, Elmes MW, Tong S, Hu K, Awwa M, Teng GYH, Jing Y, Freitag M, Gan Q, Clement T, Wei L, Sweeney JM, Joseph OM, Che J, Carbonetti GS, Wang L, Bogdan DM, Falcone J, Smietalo N, Zhou Y, Ralph B, Hsu HC, Li H, Rizzo RC, Deutsch DG, Kaczocha M, Ojima I. Yan S, et al. Among authors: wei l. Eur J Med Chem. 2018 Jun 25;154:233-252. doi: 10.1016/j.ejmech.2018.04.050. Epub 2018 May 26. Eur J Med Chem. 2018. PMID: 29803996 Free PMC article.
A biomarker framework for liver aging: the Aging Biomarker Consortium consensus statement.
Aging Biomarker Consortium; Jiang M, Zheng Z, Wang X, Chen Y, Qu J, Ding Q, Zhang W, Liu YS, Yang J, Tang W, Hou Y, He J, Wang L, Huang P, Li LC, He Z, Gao Q, Lu Q, Wei L, Wang YJ, Ju Z, Fan JG, Ruan XZ, Guan Y, Liu GH, Pei G, Li J, Wang Y. Aging Biomarker Consortium, et al. Among authors: wei l. Life Med. 2024 Jan 30;3(1):lnae004. doi: 10.1093/lifemedi/lnae004. eCollection 2024 Feb. Life Med. 2024. PMID: 39872390 Free PMC article.
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