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In vivo editing of lung stem cells for durable gene correction in mice.
Sun Y, Chatterjee S, Lian X, Traylor Z, Sattiraju SR, Xiao Y, Dilliard SA, Sung YC, Kim M, Lee SM, Moore S, Wang X, Zhang D, Wu S, Basak P, Wang J, Liu J, Mann RJ, LePage DF, Jiang W, Abid S, Hennig M, Martinez A, Wustman BA, Lockhart DJ, Jain R, Conlon RA, Drumm ML, Hodges CA, Siegwart DJ. Sun Y, et al. Among authors: lian x. Science. 2024 Jun 14;384(6701):1196-1202. doi: 10.1126/science.adk9428. Epub 2024 Jun 13. Science. 2024. PMID: 38870301
The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles.
Dilliard SA, Sun Y, Brown MO, Sung YC, Chatterjee S, Farbiak L, Vaidya A, Lian X, Wang X, Lemoff A, Siegwart DJ. Dilliard SA, et al. Among authors: lian x. J Control Release. 2023 Sep;361:361-372. doi: 10.1016/j.jconrel.2023.07.058. Epub 2023 Aug 10. J Control Release. 2023. PMID: 37536547 Free PMC article.
In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma.
Cheng Q, Farbiak L, Vaidya A, Guerrero E, Lee EE, Rose EK, Wang X, Robinson J, Lee SM, Wei T, Miller WE, Alvarez Benedicto E, Lian X, Wang RC, Siegwart DJ. Cheng Q, et al. Among authors: lian x. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2313009120. doi: 10.1073/pnas.2313009120. Epub 2023 Dec 18. Proc Natl Acad Sci U S A. 2023. PMID: 38109533 Free PMC article.
Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells.
Lian X, Chatterjee S, Sun Y, Dilliard SA, Moore S, Xiao Y, Bian X, Yamada K, Sung YC, Levine RM, Mayberry K, John S, Liu X, Smith C, Johnson LT, Wang X, Zhang CC, Liu DR, Newby GA, Weiss MJ, Yen JS, Siegwart DJ. Lian X, et al. Nat Nanotechnol. 2024 Sep;19(9):1409-1417. doi: 10.1038/s41565-024-01680-8. Epub 2024 May 23. Nat Nanotechnol. 2024. PMID: 38783058
1,645 results