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In vivo editing of lung stem cells for durable gene correction in mice.
Sun Y, Chatterjee S, Lian X, Traylor Z, Sattiraju SR, Xiao Y, Dilliard SA, Sung YC, Kim M, Lee SM, Moore S, Wang X, Zhang D, Wu S, Basak P, Wang J, Liu J, Mann RJ, LePage DF, Jiang W, Abid S, Hennig M, Martinez A, Wustman BA, Lockhart DJ, Jain R, Conlon RA, Drumm ML, Hodges CA, Siegwart DJ. Sun Y, et al. Among authors: conlon ra. Science. 2024 Jun 14;384(6701):1196-1202. doi: 10.1126/science.adk9428. Epub 2024 Jun 13. Science. 2024. PMID: 38870301
A Mouse Model of the Protease Activated Receptor 4 (PAR4) Pro310Leu Variant has Reduced Platelet Reactivity.
Han X, Knauss EA, de la Fuente M, Li W, Conlon RA, LePage DF, Jiang W, Renna SA, McKenzie SE, Nieman MT. Han X, et al. Among authors: conlon ra. bioRxiv [Preprint]. 2023 Dec 1:2023.12.01.569075. doi: 10.1101/2023.12.01.569075. bioRxiv. 2023. Update in: J Thromb Haemost. 2024 Jun;22(6):1715-1726. doi: 10.1016/j.jtha.2024.03.004 PMID: 38077081 Free PMC article. Updated. Preprint.
A W1282X cystic fibrosis mouse allows the study of pharmacological and gene-editing therapeutics to restore CFTR function.
Michicich M, Traylor Z, McCoy C, Valerio DM, Wilson A, Schneider M, Davis S, Barabas A, Mann RJ, LePage DF, Jiang W, Drumm ML, Kelley TJ, Conlon RA, Hodges CA. Michicich M, et al. Among authors: conlon ra. J Cyst Fibros. 2024 Nov 11:S1569-1993(24)01797-1. doi: 10.1016/j.jcf.2024.10.008. Online ahead of print. J Cyst Fibros. 2024. PMID: 39532588 Free article.
Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer.
Li Y, Wu S, Zhao Y, Dinh T, Jiang D, Selfridge JE, Myers G, Wang Y, Zhao X, Tomchuck S, Dubyak G, Lee RT, Estfan B, Shapiro M, Kamath S, Mohamed A, Huang SC, Huang AY, Conlon R, Krishnamurthi S, Eads J, Willis JE, Khorana AA, Bajor D, Wang Z. Li Y, et al. J Clin Invest. 2024 Jan 9;134(5):e175031. doi: 10.1172/JCI175031. J Clin Invest. 2024. PMID: 38194275 Free PMC article.
Governing nonconventional genetic experimentation.
Mehlman MJ, Conlon RA, Pearlman A. Mehlman MJ, et al. Among authors: conlon ra. J Law Biosci. 2023 Mar 9;10(1):lsad003. doi: 10.1093/jlb/lsad003. eCollection 2023 Jan-Jun. J Law Biosci. 2023. PMID: 36910719 Free PMC article.
57 results