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Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design.
Ellis D, Brunette N, Crawford KHD, Walls AC, Pham MN, Chen C, Herpoldt KL, Fiala B, Murphy M, Pettie D, Kraft JC, Malone KD, Navarro MJ, Ogohara C, Kepl E, Ravichandran R, Sydeman C, Ahlrichs M, Johnson M, Blackstone A, Carter L, Starr TN, Greaney AJ, Lee KK, Veesler D, Bloom JD, King NP. Ellis D, et al. Among authors: crawford khd. Front Immunol. 2021 Jun 29;12:710263. doi: 10.3389/fimmu.2021.710263. eCollection 2021. Front Immunol. 2021. PMID: 34267764 Free PMC article.
A human coronavirus evolves antigenically to escape antibody immunity.
Eguia RT, Crawford KHD, Stevens-Ayers T, Kelnhofer-Millevolte L, Greninger AL, Englund JA, Boeckh MJ, Bloom JD. Eguia RT, et al. Among authors: crawford khd. PLoS Pathog. 2021 Apr 8;17(4):e1009453. doi: 10.1371/journal.ppat.1009453. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33831132 Free PMC article.
Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex.
Carr CR, Crawford KHD, Murphy M, Galloway JG, Haddox HK, Matsen FA 4th, Andersen KG, King NP, Bloom JD. Carr CR, et al. Among authors: crawford khd. bioRxiv [Preprint]. 2024 Feb 6:2024.02.05.579020. doi: 10.1101/2024.02.05.579020. bioRxiv. 2024. Update in: Immunity. 2024 Sep 10;57(9):2061-2076.e11. doi: 10.1016/j.immuni.2024.06.013 PMID: 38370709 Free PMC article. Updated. Preprint.
Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with high attack rate.
Addetia A, Crawford KH, Dingens A, Zhu H, Roychoudhury P, Huang ML, Jerome KR, Bloom JD, Greninger AL. Addetia A, et al. medRxiv [Preprint]. 2020 Aug 14:2020.08.13.20173161. doi: 10.1101/2020.08.13.20173161. medRxiv. 2020. Update in: J Clin Microbiol. 2020 Oct 21;58(11):e02107-20. doi: 10.1128/JCM.02107-20 PMID: 32817980 Free PMC article. Updated. Preprint.
33 results