Rosario FJ - Search Results

1

Claudin-4 Modulates Autophagy via SLC1A5/LAT1 as a Mechanism to Regulate Micronuclei.

Villagomez FR, Lang J, Rosario FJ, Nunez-Avellaneda D, Webb P, Neville M, Woodruff ER, Bitler BG. Villagomez FR, et al. Among authors: rosario fj. Cancer Res Commun. 2024 Jul 1;4(7):1625-1642. doi: 10.1158/2767-9764.CRC-24-0240. Cancer Res Commun. 2024. PMID: 38867360 Free PMC article.

2

Gene targeting in primary human trophoblasts.

Rosario FJ, Sadovsky Y, Jansson T. Rosario FJ, et al. Placenta. 2012 Oct;33(10):754-62. doi: 10.1016/j.placenta.2012.07.003. Epub 2012 Jul 23. Placenta. 2012. PMID: 22831880 Free PMC article. Review.

3

Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling.

Rosario FJ, Urschitz J, Powell TL, Brown TL, Jansson T. Rosario FJ, et al. Clin Sci (Lond). 2023 Nov 15;137(21):1651-1664. doi: 10.1042/CS20230490. Clin Sci (Lond). 2023. PMID: 37861075 Free PMC article.

4

Trophoblast-specific overexpression of the LAT1 increases transplacental transport of essential amino acids and fetal growth in mice.

Rosario FJ, Barentsen K, Powell TL, Urschitz J, Brown TL, Kanai Y, Jansson T. Rosario FJ, et al. PNAS Nexus. 2024 Jun 18;3(6):pgae207. doi: 10.1093/pnasnexus/pgae207. eCollection 2024 Jun. PNAS Nexus. 2024. PMID: 38894879 Free PMC article.

5

mTOR folate sensing links folate availability to trophoblast cell function.

Rosario FJ, Powell TL, Jansson T. Rosario FJ, et al. J Physiol. 2017 Jul 1;595(13):4189-4206. doi: 10.1113/JP272424. Epub 2017 Jun 1. J Physiol. 2017. PMID: 28374905 Free PMC article.

6

Mechanistic Target of Rapamycin Is a Novel Molecular Mechanism Linking Folate Availability and Cell Function.

Silva E, Rosario FJ, Powell TL, Jansson T. Silva E, et al. Among authors: rosario fj. J Nutr. 2017 Jul;147(7):1237-1242. doi: 10.3945/jn.117.248823. Epub 2017 Jun 7. J Nutr. 2017. PMID: 28592519 Free PMC article. Review.

7

Mechanistic target of rapamycin (mTOR) regulates trophoblast folate uptake by modulating the cell surface expression of FR-α and the RFC.

Rosario FJ, Powell TL, Jansson T. Rosario FJ, et al. Sci Rep. 2016 Aug 26;6:31705. doi: 10.1038/srep31705. Sci Rep. 2016. PMID: 27562465 Free PMC article.

8

Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice.

Rosario FJ, Nathanielsz PW, Powell TL, Jansson T. Rosario FJ, et al. Sci Rep. 2017 Jun 21;7(1):3982. doi: 10.1038/s41598-017-03888-2. Sci Rep. 2017. PMID: 28638048 Free PMC article.

9

Impaired placental autophagy in placental malaria.

Dimasuay KG, Gong L, Rosario F, McBryde E, Spelman T, Glazier J, Rogerson SJ, Beeson JG, Jansson T, Devenish RJ, Boeuf P. Dimasuay KG, et al. PLoS One. 2017 Nov 10;12(11):e0187291. doi: 10.1371/journal.pone.0187291. eCollection 2017. PLoS One. 2017. PMID: 29125872 Free PMC article.

10

Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction.

Jansson T, Castillo-Castrejon M, Gupta MB, Powell TL, Rosario FJ. Jansson T, et al. Among authors: rosario fj. Clin Sci (Lond). 2020 Jan 17;134(1):53-70. doi: 10.1042/CS20190794. Clin Sci (Lond). 2020. PMID: 31825077 Free PMC article.

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