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Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin.
Liu X, Onda M, Watson N, Hassan R, Ho M, Bera TK, Wei J, Chakraborty A, Beers R, Zhou Q, Shajahan A, Azadi P, Zhan J, Xia D, Pastan I. Liu X, et al. Among authors: chakraborty a. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2202439119. doi: 10.1073/pnas.2202439119. Epub 2022 May 5. Proc Natl Acad Sci U S A. 2022. PMID: 35512094 Free PMC article.
12-Lipoxygenase inhibition improves glucose homeostasis and obesity-associated inflammation in human gene replacement mice.
Kaylan KB, Nargis T, Figatner K, Wang JE, Pratuangtham S, Chakraborty A, Casimiro I, Nadler JL, Boxer MB, Maloney DJ, Anderson RM, Mirmira RG, Tersey SA. Kaylan KB, et al. Among authors: chakraborty a. bioRxiv [Preprint]. 2025 Jan 13:2025.01.10.632274. doi: 10.1101/2025.01.10.632274. bioRxiv. 2025. PMID: 39868153 Free PMC article. Preprint.
Designed mosaic nanoparticles enhance cross-reactive immune responses in mice.
Wang E, Cohen AA, Caldera LF, Keeffe JR, Rorick AV, Adia YM, Gnanapragasam PNP, Bjorkman PJ, Chakraborty AK. Wang E, et al. Among authors: chakraborty ak. Cell. 2025 Jan 16:S0092-8674(24)01428-4. doi: 10.1016/j.cell.2024.12.015. Online ahead of print. Cell. 2025. PMID: 39855201 Free article.
2,649 results