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A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation and shortened lifespan.
Ortega-Molina A, Lebrero-Fernández C, Sanz A, Calvo-Rubio M, Deleyto-Seldas N, de Prado-Rivas L, Plata-Gómez AB, Fernández-Florido E, González-García P, Vivas-García Y, Sánchez García E, Graña-Castro O, Price NL, Aroca-Crevillén A, Caleiras E, Monleón D, Borrás C, Casanova-Acebes M, de Cabo R, Efeyan A. Ortega-Molina A, et al. Among authors: borras c. Nat Aging. 2024 Aug;4(8):1102-1120. doi: 10.1038/s43587-024-00635-x. Epub 2024 Jun 7. Nat Aging. 2024. PMID: 38849535 Free PMC article.
RasGrf1 deficiency delays aging in mice.
Borrás C, Monleón D, López-Grueso R, Gambini J, Orlando L, Pallardó FV, Santos E, Viña J, Font de Mora J. Borrás C, et al. Aging (Albany NY). 2011 Mar;3(3):262-76. doi: 10.18632/aging.100279. Aging (Albany NY). 2011. PMID: 21422498 Free PMC article.
Delayed ageing through damage protection by the Arf/p53 pathway.
Matheu A, Maraver A, Klatt P, Flores I, Garcia-Cao I, Borras C, Flores JM, Viña J, Blasco MA, Serrano M. Matheu A, et al. Among authors: borras c. Nature. 2007 Jul 19;448(7151):375-9. doi: 10.1038/nature05949. Nature. 2007. PMID: 17637672
Anti-aging activity of the Ink4/Arf locus.
Matheu A, Maraver A, Collado M, Garcia-Cao I, Cañamero M, Borras C, Flores JM, Klatt P, Viña J, Serrano M. Matheu A, et al. Among authors: borras c. Aging Cell. 2009 Apr;8(2):152-61. doi: 10.1111/j.1474-9726.2009.00458.x. Aging Cell. 2009. PMID: 19239418 Free article.
Editorial: Women in Aging Research.
Borrás C, Haynes L, Zhang J. Borrás C, et al. Front Aging. 2022 May 20;3:913488. doi: 10.3389/fragi.2022.913488. eCollection 2022. Front Aging. 2022. PMID: 35821849 Free PMC article. No abstract available.
197 results