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Ketogenic diet administration later in life improves memory by modifying the synaptic cortical proteome via the PKA signaling pathway in aging mice.
Acuña-Catalán D, Shah S, Wehrfritz C, Nomura M, Acevedo A, Olmos C, Quiroz G, Huerta H, Bons J, Ampuero E, Wyneken U, Sanhueza M, Arancibia F, Contreras D, Cárdenas JC, Morales B, Schilling B, Newman JC, González-Billault C. Acuña-Catalán D, et al. Among authors: newman jc. Cell Rep Med. 2024 Jun 18;5(6):101593. doi: 10.1016/j.xcrm.2024.101593. Epub 2024 Jun 5. Cell Rep Med. 2024. PMID: 38843842 Free PMC article.
β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain.
Madhavan SS, Roa Diaz S, Peralta S, Nomura M, King CD, Lin A, Bhaumik D, Shah S, Blade T, Gray W, Chamoli M, Eap B, Panda O, Diaz D, Garcia TY, Stubbs BJ, Lithgow GJ, Schilling B, Verdin E, Chaudhuri AR, Newman JC. Madhavan SS, et al. Among authors: newman jc. bioRxiv [Preprint]. 2023 Jul 3:2023.07.03.547547. doi: 10.1101/2023.07.03.547547. bioRxiv. 2023. Update in: Cell Chem Biol. 2024 Nov 25:S2451-9456(24)00459-8. doi: 10.1016/j.chembiol.2024.11.001 PMID: 37461525 Free PMC article. Updated. Preprint.
A ketogenic diet reduces age-induced chronic neuroinflammation in mice Running title: ketogenic diet and brain inflammaging.
Nomura M, Murad NF, Madhavan SS, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC. Nomura M, et al. Among authors: newman jc. bioRxiv [Preprint]. 2023 Dec 4:2023.12.01.569598. doi: 10.1101/2023.12.01.569598. bioRxiv. 2023. Update in: Aging Biol. 2024;2:20240038. doi: 10.59368/agingbio.20240038 PMID: 38106160 Free PMC article. Updated. Preprint.
A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: newman jc. Cell Rep. 2024 Nov 26;43(11):114891. doi: 10.1016/j.celrep.2024.114891. Epub 2024 Nov 4. Cell Rep. 2024. PMID: 39500329 Free PMC article.
β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain.
Madhavan SS, Roa Diaz S, Peralta S, Nomura M, King CD, Ceyhan KE, Lin A, Bhaumik D, Foulger AC, Shah S, Blade T, Gray W, Chamoli M, Eap B, Panda O, Diaz D, Garcia TY, Stubbs BJ, Ulrich SM, Lithgow GJ, Schilling B, Verdin E, Chaudhuri AR, Newman JC. Madhavan SS, et al. Among authors: newman jc. Cell Chem Biol. 2024 Nov 25:S2451-9456(24)00459-8. doi: 10.1016/j.chembiol.2024.11.001. Online ahead of print. Cell Chem Biol. 2024. PMID: 39626664 Free article.
Ketogenic Diet Reduces Age-Induced Chronic Neuroinflammation in Mice.
Nomura M, Murad NF, Madhavan SS, Mu WC, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC. Nomura M, et al. Among authors: newman jc. Aging Biol. 2024;2:20240038. doi: 10.59368/agingbio.20240038. Epub 2024 Dec 16. Aging Biol. 2024. PMID: 39697898 Free PMC article.
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.
Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, Hellerstein M, Goetzman ES, Gibson BW, Verdin E. Rardin MJ, et al. Among authors: newman jc. Cell Metab. 2013 Dec 3;18(6):920-33. doi: 10.1016/j.cmet.2013.11.013. Cell Metab. 2013. PMID: 24315375 Free PMC article.
Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells.
Ang QY, Alexander M, Newman JC, Tian Y, Cai J, Upadhyay V, Turnbaugh JA, Verdin E, Hall KD, Leibel RL, Ravussin E, Rosenbaum M, Patterson AD, Turnbaugh PJ. Ang QY, et al. Among authors: newman jc. Cell. 2020 Jun 11;181(6):1263-1275.e16. doi: 10.1016/j.cell.2020.04.027. Epub 2020 May 20. Cell. 2020. PMID: 32437658 Free PMC article.
123 results