Werz O - Search Results

1

Bromo-substituted indirubins for inhibition of protein kinase-mediated signalling involved in inflammatory mediator release in human monocytes.

Bachmann V, Schädel P, Westhoff J, Perić M, Schömberg F, Skaltsounis AL, Höppener S, Pantsar T, Fischer D, Vilotijević I, Werz O. Bachmann V, et al. Among authors: werz o. Bioorg Chem. 2024 Aug;149:107470. doi: 10.1016/j.bioorg.2024.107470. Epub 2024 May 23. Bioorg Chem. 2024. PMID: 38838619 Free article.

2

Melleolides induce rapid cell death in human primary monocytes and cancer cells.

Bohnert M, Scherer O, Wiechmann K, König S, Dahse HM, Hoffmeister D, Werz O. Bohnert M, et al. Among authors: werz o. Bioorg Med Chem. 2014 Aug 1;22(15):3856-61. doi: 10.1016/j.bmc.2014.06.032. Epub 2014 Jun 25. Bioorg Med Chem. 2014. PMID: 25028062

3

Identification of pirinixic acid derivatives bearing a 2-aminothiazole moiety combines dual PPARα/γ activation and dual 5-LO/mPGES-1 inhibition.

Hanke T, Lamers C, Gomez RC, Schneider G, Werz O, Schubert-Zsilavecz M. Hanke T, et al. Among authors: werz o. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3757-63. doi: 10.1016/j.bmcl.2014.06.077. Epub 2014 Jul 3. Bioorg Med Chem Lett. 2014. PMID: 25037914

4

Discovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol.

Noha SM, Fischer K, Koeberle A, Garscha U, Werz O, Schuster D. Noha SM, et al. Among authors: werz o. Bioorg Med Chem. 2015 Aug 1;23(15):4839-4845. doi: 10.1016/j.bmc.2015.05.045. Epub 2015 Jun 1. Bioorg Med Chem. 2015. PMID: 26088337 Free PMC article.

5

The acylphloroglucinols hyperforin and myrtucommulone A cause mitochondrial dysfunctions in leukemic cells by direct interference with mitochondria.

Wiechmann K, Müller H, Fischer D, Jauch J, Werz O. Wiechmann K, et al. Among authors: werz o. Apoptosis. 2015 Nov;20(11):1508-17. doi: 10.1007/s10495-015-1170-9. Apoptosis. 2015. PMID: 26386573

6

Evaluation of Dual 5-Lipoxygenase/Microsomal Prostaglandin E2 Synthase-1 Inhibitory Effect of Natural and Synthetic Acronychia-Type Isoprenylated Acetophenones.

Svouraki A, Garscha U, Kouloura E, Pace S, Pergola C, Krauth V, Rossi A, Sautebin L, Halabalaki M, Werz O, Gaboriaud-Kolar N, Skaltsounis AL. Svouraki A, et al. Among authors: werz o. J Nat Prod. 2017 Mar 24;80(3):699-706. doi: 10.1021/acs.jnatprod.6b01008. Epub 2017 Feb 27. J Nat Prod. 2017. PMID: 28240894

7

Triterpene Acids from Frankincense and Semi-Synthetic Derivatives That Inhibit 5-Lipoxygenase and Cathepsin G.

Koeberle A, Henkel A, Verhoff M, Tausch L, König S, Fischer D, Kather N, Seitz S, Paul M, Jauch J, Werz O. Koeberle A, et al. Among authors: werz o. Molecules. 2018 Feb 24;23(2):506. doi: 10.3390/molecules23020506. Molecules. 2018. PMID: 29495286 Free PMC article.

8

Process control and scale-up of modified bacterial cellulose production for tailor-made anti-inflammatory drug delivery systems.

Beekmann U, Schmölz L, Lorkowski S, Werz O, Thamm J, Fischer D, Kralisch D. Beekmann U, et al. Among authors: werz o. Carbohydr Polym. 2020 May 15;236:116062. doi: 10.1016/j.carbpol.2020.116062. Epub 2020 Feb 22. Carbohydr Polym. 2020. PMID: 32172877

9

Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction.

Gebert N, Cheng CW, Kirkpatrick JM, Di Fraia D, Yun J, Schädel P, Pace S, Garside GB, Werz O, Rudolph KL, Jasper H, Yilmaz ÖH, Ori A. Gebert N, et al. Among authors: werz o. Cell Rep. 2020 Apr 28;31(4):107565. doi: 10.1016/j.celrep.2020.107565. Cell Rep. 2020. PMID: 32348758 Free PMC article.

10

Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity.

Shkodra-Pula B, Kretzer C, Jordan PM, Klemm P, Koeberle A, Pretzel D, Banoglu E, Lorkowski S, Wallert M, Höppener S, Stumpf S, Vollrath A, Schubert S, Werz O, Schubert US. Shkodra-Pula B, et al. Among authors: werz o. J Nanobiotechnology. 2020 May 14;18(1):73. doi: 10.1186/s12951-020-00620-7. J Nanobiotechnology. 2020. PMID: 32408877 Free PMC article.

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