Dobert JP - Search Results

1

Late-onset Krabbe disease presenting as spastic paraplegia - implications of GCase and CTSB/D.

Mächtel R, Dobert JP, Hehr U, Weiss A, Kettwig M, Laugwitz L, Groeschel S, Schmidt M, Arnold P, Regensburger M, Zunke F. Mächtel R, et al. Among authors: dobert jp. Ann Clin Transl Neurol. 2024 Jul;11(7):1715-1731. doi: 10.1002/acn3.52078. Epub 2024 Jun 4. Ann Clin Transl Neurol. 2024. PMID: 38837642 Free PMC article.

2

Activation and Purification of ß-Glucocerebrosidase by Exploiting its Transporter LIMP-2 - Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease.

Dobert JP, Bub S, Mächtel R, Januliene D, Steger L, Regensburger M, Wilfling S, Chen JX, Dejung M, Plötz S, Hehr U, Moeller A, Arnold P, Zunke F. Dobert JP, et al. Adv Sci (Weinh). 2024 Jul;11(25):e2401641. doi: 10.1002/advs.202401641. Epub 2024 Apr 26. Adv Sci (Weinh). 2024. PMID: 38666485 Free PMC article.

3

Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models.

Drobny A, Boros FA, Balta D, Prieto Huarcaya S, Caylioglu D, Qazi N, Vandrey J, Schneider Y, Dobert JP, Pitcairn C, Mazzulli JR, Zunke F. Drobny A, et al. Among authors: dobert jp. Transl Neurodegener. 2023 Jun 13;12(1):31. doi: 10.1186/s40035-023-00363-z. Transl Neurodegener. 2023. PMID: 37312133 Free PMC article.

4

From Lysosomal Storage Disorders to Parkinson's Disease - Challenges and Opportunities.

Mächtel R, Boros FA, Dobert JP, Arnold P, Zunke F. Mächtel R, et al. Among authors: dobert jp. J Mol Biol. 2023 Jun 15;435(12):167932. doi: 10.1016/j.jmb.2022.167932. Epub 2022 Dec 23. J Mol Biol. 2023. PMID: 36572237 Free article. Review.

5

Cancer-type organic anion transporting polypeptide 1B3 (Ct-OATP1B3) is localized in lysosomes and mediates resistance against kinase inhibitors.

Haberkorn B, Oswald S, Kehl N, Gessner A, Taudte RV, Dobert JP, Zunke F, Fromm MF, König J. Haberkorn B, et al. Among authors: dobert jp. Mol Pharmacol. 2022 Sep 27:MOLPHARM-AR-2022-000539. doi: 10.1124/molpharm.122.000539. Online ahead of print. Mol Pharmacol. 2022. PMID: 36167426 Free article.

6

Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models.

Prieto Huarcaya S, Drobny A, Marques ARA, Di Spiezio A, Dobert JP, Balta D, Werner C, Rizo T, Gallwitz L, Bub S, Stojkovska I, Belur NR, Fogh J, Mazzulli JR, Xiang W, Fulzele A, Dejung M, Sauer M, Winner B, Rose-John S, Arnold P, Saftig P, Zunke F. Prieto Huarcaya S, et al. Among authors: dobert jp. Autophagy. 2022 May;18(5):1127-1151. doi: 10.1080/15548627.2022.2045534. Epub 2022 Apr 28. Autophagy. 2022. PMID: 35287553 Free PMC article.

7

Corrigendum: Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.

Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F. Bunk J, et al. Among authors: dobert jp. Front Cell Dev Biol. 2021 Jun 23;9:671532. doi: 10.3389/fcell.2021.671532. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34249927 Free PMC article.

8

Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.

Bunk J, Prieto Huarcaya S, Drobny A, Dobert JP, Walther L, Rose-John S, Arnold P, Zunke F. Bunk J, et al. Among authors: dobert jp. Front Cell Dev Biol. 2021 Feb 11;9:581805. doi: 10.3389/fcell.2021.581805. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33681191 Free PMC article.

9

Functional Characterization of Colon-Cancer-Associated Variants in ADAM17 Affecting the Catalytic Domain.

Dobert JP, Cabron AS, Arnold P, Pavlenko E, Rose-John S, Zunke F. Dobert JP, et al. Biomedicines. 2020 Oct 30;8(11):463. doi: 10.3390/biomedicines8110463. Biomedicines. 2020. PMID: 33143292 Free PMC article.

10

Functional Characterization of Colon Cancer-Associated Mutations in ADAM17: Modifications in the Pro-Domain Interfere with Trafficking and Maturation.

Pavlenko E, Cabron AS, Arnold P, Dobert JP, Rose-John S, Zunke F. Pavlenko E, et al. Among authors: dobert jp. Int J Mol Sci. 2019 May 4;20(9):2198. doi: 10.3390/ijms20092198. Int J Mol Sci. 2019. PMID: 31060243 Free PMC article. Review.

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