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The DNA Methyltransferase Inhibitor 5-Aza-4'-thio-2'-Deoxycytidine Induces C>G Transversions and Acute Lymphoid Leukemia Development.
Cancer Res. 2024 Aug 1;84(15):2518-2532. doi: 10.1158/0008-5472.CAN-23-2785.
Cancer Res. 2024.
PMID: 38832931
5-Aza-4'-thio-2'-deoxycytidine induces C>G transversions in a specific trinucleotide context and leads to acute lymphoid leukemia.
Aplan P, Bertoli R, Chung YJ, Difilippantonio M, Wokasch A, Marasco M, Klimaszewski H, Garber S, Zhu Y, Walker R, Cao D, Doroshow J, Meltzer P.
Aplan P, et al.
Res Sq [Preprint]. 2023 Dec 19:rs.3.rs-3186246. doi: 10.21203/rs.3.rs-3186246/v1.
Res Sq. 2023.
PMID: 38168433
Free PMC article.
Preprint.
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