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447 results

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The DNA Methyltransferase Inhibitor 5-Aza-4'-thio-2'-Deoxycytidine Induces C>G Transversions and Acute Lymphoid Leukemia Development.
Bertoli RM, Chung YJ, Difilippantonio MJ, Wokasch A, Marasco MRB, Klimaszewski H, Gammell S, Zhu YJ, Walker RL, Cao D, Khanna A, Walter MJ, Doroshow JH, Meltzer PS, Aplan PD. Bertoli RM, et al. Among authors: doroshow jh. Cancer Res. 2024 Aug 1;84(15):2518-2532. doi: 10.1158/0008-5472.CAN-23-2785. Cancer Res. 2024. PMID: 38832931
CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute.
Zoppoli G, Solier S, Reinhold WC, Liu H, Connelly JW Jr, Monks A, Shoemaker RH, Abaan OD, Davis SR, Meltzer PS, Doroshow JH, Pommier Y. Zoppoli G, et al. Among authors: doroshow jh. Oncogene. 2012 Jan 26;31(4):403-18. doi: 10.1038/onc.2011.283. Epub 2011 Jul 18. Oncogene. 2012. PMID: 21765476 Free PMC article.
Genome-wide depletion of replication initiation events in highly transcribed regions.
Martin MM, Ryan M, Kim R, Zakas AL, Fu H, Lin CM, Reinhold WC, Davis SR, Bilke S, Liu H, Doroshow JH, Reimers MA, Valenzuela MS, Pommier Y, Meltzer PS, Aladjem MI. Martin MM, et al. Among authors: doroshow jh. Genome Res. 2011 Nov;21(11):1822-32. doi: 10.1101/gr.124644.111. Epub 2011 Aug 3. Genome Res. 2011. PMID: 21813623 Free PMC article.
The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.
Abaan OD, Polley EC, Davis SR, Zhu YJ, Bilke S, Walker RL, Pineda M, Gindin Y, Jiang Y, Reinhold WC, Holbeck SL, Simon RM, Doroshow JH, Pommier Y, Meltzer PS. Abaan OD, et al. Among authors: doroshow jh. Cancer Res. 2013 Jul 15;73(14):4372-82. doi: 10.1158/0008-5472.CAN-12-3342. Epub 2013 Jul 15. Cancer Res. 2013. PMID: 23856246 Free PMC article.
NCI-60 whole exome sequencing and pharmacological CellMiner analyses.
Reinhold WC, Varma S, Sousa F, Sunshine M, Abaan OD, Davis SR, Reinhold SW, Kohn KW, Morris J, Meltzer PS, Doroshow JH, Pommier Y. Reinhold WC, et al. Among authors: doroshow jh. PLoS One. 2014 Jul 17;9(7):e101670. doi: 10.1371/journal.pone.0101670. eCollection 2014. PLoS One. 2014. PMID: 25032700 Free PMC article.
The NCI-60 Methylome and Its Integration into CellMiner.
Reinhold WC, Varma S, Sunshine M, Rajapakse V, Luna A, Kohn KW, Stevenson H, Wang Y, Heyn H, Nogales V, Moran S, Goldstein DJ, Doroshow JH, Meltzer PS, Esteller M, Pommier Y. Reinhold WC, et al. Among authors: doroshow jh. Cancer Res. 2017 Feb 1;77(3):601-612. doi: 10.1158/0008-5472.CAN-16-0655. Epub 2016 Dec 6. Cancer Res. 2017. PMID: 27923837 Free PMC article.
Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis).
Kummar S, O'Sullivan Coyne G, Do KT, Turkbey B, Meltzer PS, Polley E, Choyke PL, Meehan R, Vilimas R, Horneffer Y, Juwara L, Lih A, Choudhary A, Mitchell SA, Helman LJ, Doroshow JH, Chen AP. Kummar S, et al. Among authors: doroshow jh. J Clin Oncol. 2017 May 10;35(14):1561-1569. doi: 10.1200/JCO.2016.71.1994. Epub 2017 Mar 28. J Clin Oncol. 2017. PMID: 28350521 Free PMC article. Clinical Trial.
RNA Sequencing of the NCI-60: Integration into CellMiner and CellMiner CDB.
Reinhold WC, Varma S, Sunshine M, Elloumi F, Ofori-Atta K, Lee S, Trepel JB, Meltzer PS, Doroshow JH, Pommier Y. Reinhold WC, et al. Among authors: doroshow jh. Cancer Res. 2019 Jul 1;79(13):3514-3524. doi: 10.1158/0008-5472.CAN-18-2047. Epub 2019 May 21. Cancer Res. 2019. PMID: 31113817 Free PMC article.
IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells.
Wu Y, Konaté MM, Lu J, Makhlouf H, Chuaqui R, Antony S, Meitzler JL, Difilippantonio MJ, Liu H, Juhasz A, Jiang G, Dahan I, Roy K, Doroshow JH. Wu Y, et al. Among authors: doroshow jh. J Immunol. 2019 Nov 1;203(9):2532-2544. doi: 10.4049/jimmunol.1800469. Epub 2019 Sep 23. J Immunol. 2019. PMID: 31548328 Free PMC article.
447 results