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The DNA Methyltransferase Inhibitor 5-Aza-4'-thio-2'-Deoxycytidine Induces C>G Transversions and Acute Lymphoid Leukemia Development.
Cancer Res. 2024 Aug 1;84(15):2518-2532. doi: 10.1158/0008-5472.CAN-23-2785.
Cancer Res. 2024.
PMID: 38832931
Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context.
Matsukawa T, Yin M, Baslan T, Chung YJ, Cao D, Bertoli R, Zhu YJ, Walker RL, Freeland A, Knudsen E, Lowe SW, Meltzer PS, Aplan PD.
Matsukawa T, et al.
FASEB J. 2022 Sep;36(9):e22430. doi: 10.1096/fj.202200061RR.
FASEB J. 2022.
PMID: 35920299
Free PMC article.
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5-Aza-4'-thio-2'-deoxycytidine induces C>G transversions in a specific trinucleotide context and leads to acute lymphoid leukemia.
Aplan P, Bertoli R, Chung YJ, Difilippantonio M, Wokasch A, Marasco M, Klimaszewski H, Garber S, Zhu Y, Walker R, Cao D, Doroshow J, Meltzer P.
Aplan P, et al.
Res Sq [Preprint]. 2023 Dec 19:rs.3.rs-3186246. doi: 10.21203/rs.3.rs-3186246/v1.
Res Sq. 2023.
PMID: 38168433
Free PMC article.
Preprint.
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The Ribbon-Helix-Helix Domain Protein CdrS Regulates the Tubulin Homolog ftsZ2 To Control Cell Division in Archaea.
Darnell CL, Zheng J, Wilson S, Bertoli RM, Bisson-Filho AW, Garner EC, Schmid AK.
Darnell CL, et al. Among authors: bertoli rm.
mBio. 2020 Aug 11;11(4):e01007-20. doi: 10.1128/mBio.01007-20.
mBio. 2020.
PMID: 32788376
Free PMC article.
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