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An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination.
Barclay KM, Abduljawad N, Cheng Z, Kim MW, Zhou L, Yang J, Rustenhoven J, Mazzitelli JA, Smyth LCD, Kapadia D, Brioschi S, Beatty W, Hou J, Saligrama N, Colonna M, Yu G, Kipnis J, Li Q. Barclay KM, et al. Among authors: brioschi s. Immunity. 2024 Jun 11;57(6):1394-1412.e8. doi: 10.1016/j.immuni.2024.05.005. Epub 2024 May 30. Immunity. 2024. PMID: 38821054 Free article.
Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease.
Garcia P, Jürgens-Wemheuer W, Uriarte Huarte O, Michelucci A, Masuch A, Brioschi S, Weihofen A, Koncina E, Coowar D, Heurtaux T, Glaab E, Balling R, Sousa C, Kaoma T, Nicot N, Pfander T, Schulz-Schaeffer W, Allouche A, Fischer N, Biber K, Kleine-Borgmann F, Mittelbronn M, Ostaszewski M, Schmit KJ, Buttini M. Garcia P, et al. Among authors: brioschi s. Glia. 2022 May;70(5):935-960. doi: 10.1002/glia.24149. Epub 2022 Jan 29. Glia. 2022. PMID: 35092321 Free PMC article.
The CNS Immune-Privilege Goes Down the Drain(age).
Brioschi S, Colonna M. Brioschi S, et al. Trends Pharmacol Sci. 2019 Jan;40(1):1-3. doi: 10.1016/j.tips.2018.11.006. Epub 2018 Dec 5. Trends Pharmacol Sci. 2019. PMID: 30528463
Fifty Shades of Microglia.
Brioschi S, Peng V, Colonna M. Brioschi S, et al. Trends Neurosci. 2019 Jul;42(7):440-443. doi: 10.1016/j.tins.2019.03.010. Epub 2019 Apr 18. Trends Neurosci. 2019. PMID: 31005331
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.
Molgora M, Esaulova E, Vermi W, Hou J, Chen Y, Luo J, Brioschi S, Bugatti M, Omodei AS, Ricci B, Fronick C, Panda SK, Takeuchi Y, Gubin MM, Faccio R, Cella M, Gilfillan S, Unanue ER, Artyomov MN, Schreiber RD, Colonna M. Molgora M, et al. Among authors: brioschi s. Cell. 2020 Aug 20;182(4):886-900.e17. doi: 10.1016/j.cell.2020.07.013. Epub 2020 Aug 11. Cell. 2020. PMID: 32783918 Free PMC article.
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging.
Mogilenko DA, Shpynov O, Andhey PS, Arthur L, Swain A, Esaulova E, Brioschi S, Shchukina I, Kerndl M, Bambouskova M, Yao Z, Laha A, Zaitsev K, Burdess S, Gillfilan S, Stewart SA, Colonna M, Artyomov MN. Mogilenko DA, et al. Among authors: brioschi s. Immunity. 2021 Jan 12;54(1):99-115.e12. doi: 10.1016/j.immuni.2020.11.005. Epub 2020 Dec 2. Immunity. 2021. PMID: 33271118 Free article.
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma.
Cugurra A, Mamuladze T, Rustenhoven J, Dykstra T, Beroshvili G, Greenberg ZJ, Baker W, Papadopoulos Z, Drieu A, Blackburn S, Kanamori M, Brioschi S, Herz J, Schuettpelz LG, Colonna M, Smirnov I, Kipnis J. Cugurra A, et al. Among authors: brioschi s. Science. 2021 Jul 23;373(6553):eabf7844. doi: 10.1126/science.abf7844. Epub 2021 Jun 3. Science. 2021. PMID: 34083447 Free PMC article.
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders.
Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M. Brioschi S, et al. Science. 2021 Jul 23;373(6553):eabf9277. doi: 10.1126/science.abf9277. Epub 2021 Jun 3. Science. 2021. PMID: 34083450 Free PMC article.
48 results