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Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target.
Bielinski M, Henderson LR, Yosaatmadja Y, Swift LP, Baddock HT, Bowen MJ, Brem J, Jones PS, McElroy SP, Morrison A, Speake M, van Boeckel S, van Doornmalen E, van Groningen J, van den Hurk H, Gileadi O, Newman JA, McHugh PJ, Schofield CJ. Bielinski M, et al. Among authors: van groningen j. Chem Sci. 2024 Apr 30;15(21):8227-8241. doi: 10.1039/d4sc00367e. eCollection 2024 May 29. Chem Sci. 2024. PMID: 38817593 Free PMC article.
Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation.
Fernández DI, Provenzale I, Cheung HYF, van Groningen J, Tullemans BME, Veninga A, Dunster JL, Honarnejad S, van den Hurk H, Kuijpers MJE, Heemskerk JWM. Fernández DI, et al. Among authors: van groningen j. iScience. 2021 Dec 31;25(1):103718. doi: 10.1016/j.isci.2021.103718. eCollection 2022 Jan 21. iScience. 2021. PMID: 35072010 Free PMC article.
High-Throughput Fluorescence-Based Activity Assay for Arginase-1.
Grobben Y, Willemsen-Seegers N, Uitdehaag JCM, de Man J, van Groningen J, Friesen J, van den Hurk H, Buijsman RC, Zaman GJR. Grobben Y, et al. Among authors: van groningen j. SLAS Discov. 2020 Oct;25(9):1018-1025. doi: 10.1177/2472555220919340. Epub 2020 May 16. SLAS Discov. 2020. PMID: 32418491 Free article.
Identifying best performing hospitals in colorectal cancer care; is it possible?
van Groningen JT, Ceyisakar IE, Gietelink L, Henneman D, van der Harst E, Westerterp M, Marang-van de Mheen PJ, Tollenaar RAEM, Lingsma H, Wouters MWJM; Dutch Surgical Colorectal Audit Group. van Groningen JT, et al. Eur J Surg Oncol. 2020 Jun;46(6):1144-1150. doi: 10.1016/j.ejso.2020.02.024. Epub 2020 Feb 21. Eur J Surg Oncol. 2020. PMID: 32178963
57 results