Ling Y - Search Results

1

Development of Novel β-Carboline/Furylmalononitrile Hybrids as Type I/II Photosensitizers with Chemo-Photodynamic Therapy and Minimal Toxicity.

Xie X, Sun T, Pan H, Ji D, Xu Z, Gao G, Miao J, Wang L, Zhang Y, Liu J, Ling Y, Su X. Xie X, et al. Among authors: ling y. Mol Pharm. 2024 Jul 1;21(7):3553-3565. doi: 10.1021/acs.molpharmaceut.4c00238. Epub 2024 May 30. Mol Pharm. 2024. PMID: 38816926

2

Hybrids from Farnesylthiosalicylic Acid and Hydroxamic Acid as Dual Ras-Related Signaling and Histone Deacetylase (HDAC) Inhibitors: Design, Synthesis and Biological Evaluation.

Ling Y, Wang X, Wang C, Xu C, Zhang W, Zhang Y, Zhang Y. Ling Y, et al. ChemMedChem. 2015 Jun;10(6):971-6. doi: 10.1002/cmdc.201500019. Epub 2015 Apr 16. ChemMedChem. 2015. PMID: 25882299

3

Novel β-Carboline/Hydroxamic Acid Hybrids Targeting Both Histone Deacetylase and DNA Display High Anticancer Activity via Regulation of the p53 Signaling Pathway.

Ling Y, Xu C, Luo L, Cao J, Feng J, Xue Y, Zhu Q, Ju C, Li F, Zhang Y, Zhang Y, Ling X. Ling Y, et al. Among authors: ling x. J Med Chem. 2015 Dec 10;58(23):9214-27. doi: 10.1021/acs.jmedchem.5b01052. Epub 2015 Nov 24. J Med Chem. 2015. PMID: 26555243

4

Design, synthesis and biological evaluation of hybrids of β-carboline and salicylic acid as potential anticancer and apoptosis inducing agents.

Xu QB, Chen XF, Feng J, Miao JF, Liu J, Liu FT, Niu BX, Cai JY, Huang C, Zhang Y, Ling Y. Xu QB, et al. Among authors: ling y. Sci Rep. 2016 Nov 8;6:36238. doi: 10.1038/srep36238. Sci Rep. 2016. PMID: 27824091 Free PMC article.

5

Design and Synthesis of C3-Substituted β-Carboline-Based Histone Deacetylase Inhibitors with Potent Antitumor Activities.

Ling Y, Feng J, Luo L, Guo J, Peng Y, Wang T, Ge X, Xu Q, Wang X, Dai H, Zhang Y. Ling Y, et al. ChemMedChem. 2017 May 9;12(9):646-651. doi: 10.1002/cmdc.201700133. Epub 2017 Apr 20. ChemMedChem. 2017. PMID: 28425177

6

Development of novel β-carboline-based hydroxamate derivatives as HDAC inhibitors with antiproliferative and antimetastatic activities in human cancer cells.

Ling Y, Guo J, Yang Q, Zhu P, Miao J, Gao W, Peng Y, Yang J, Xu K, Xiong B, Liu G, Tao J, Luo L, Zhu Q, Zhang Y. Ling Y, et al. Eur J Med Chem. 2018 Jan 20;144:398-409. doi: 10.1016/j.ejmech.2017.12.061. Epub 2017 Dec 20. Eur J Med Chem. 2018. PMID: 29288941

7

A novel harmine derivative, N-(4-(hydroxycarbamoyl)benzyl)-1-(4- methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxamide (HBC), as histone deacetylase inhibitor: in vitro antiproliferation, apoptosis induction, cell cycle arrest, and antimetastatic effects.

Miao JF, Peng YF, Chen S, Gao WJ, Yang QX, Zhu P, Guo J, Tao J, Luo L, Zhang Y, Ling Y. Miao JF, et al. Among authors: ling y. Eur J Pharmacol. 2018 Apr 5;824:78-88. doi: 10.1016/j.ejphar.2018.02.004. Epub 2018 Feb 9. Eur J Pharmacol. 2018. PMID: 29428472

8

Straightforward synthesis of quinolines from enones and 2-aminobenzyl alcohols using an iridium-catalyzed transfer hydrogenative strategy.

Xiong B, Wang Y, Liu Y, Bao Y, Liu Z, Zhang Y, Ling Y. Xiong B, et al. Among authors: ling y. Org Biomol Chem. 2018 Aug 8;16(31):5707-5711. doi: 10.1039/c8ob01321g. Org Biomol Chem. 2018. PMID: 30047973

9

Development of novel β-carboline-based hydroxamate derivatives as HDAC inhibitors with DNA damage and apoptosis inducing abilities.

Liu J, Wang T, Wang X, Luo L, Guo J, Peng Y, Xu Q, Miao J, Zhang Y, Ling Y. Liu J, et al. Among authors: ling y. Medchemcomm. 2017 Mar 29;8(6):1213-1219. doi: 10.1039/c6md00681g. eCollection 2017 Jun 1. Medchemcomm. 2017. PMID: 30108831 Free PMC article.

10

Design, Synthesis, and Biological Evaluation of Novel Thiazolyl Substituted Bis-pyrazole Oxime Derivatives with Potent Antitumor Activities by Selectively Inducing Apoptosis and ROS in Cancer Cells.

Xiong B, Chen S, Zhu P, Huang M, Gao W, Zhu R, Qian J, Peng Y, Zhang Y, Dai H, Ling Y. Xiong B, et al. Among authors: ling y. Med Chem. 2019;15(7):743-754. doi: 10.2174/1573406414666180827112724. Med Chem. 2019. PMID: 30147012

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