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Page 1
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis.
Rapacciuolo P, Finamore C, Giorgio CD, Fiorillo B, Massa C, Urbani G, Marchianò S, Bordoni M, Cassiano C, Morretta E, Spinelli L, Lupia A, Moraca F, Biagioli M, Sepe V, Monti MC, Catalanotti B, Fiorucci S, Zampella A. Rapacciuolo P, et al. Among authors: moraca f. J Med Chem. 2024 Oct 24;67(20):18334-18355. doi: 10.1021/acs.jmedchem.4c01651. Epub 2024 Oct 9. J Med Chem. 2024. PMID: 39382988
Author Correction: Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.
Rinaldi L, Donne RD, Catalanotti B, Torres-Quesada O, Enzler F, Moraca F, Nisticò R, Chiuso F, Piccinin S, Bachmann V, Lindner HH, Garbi C, Scorziello A, Russo NA, Synofzik M, Stelzl U, Annunziato L, Stefan E, Feliciello A. Rinaldi L, et al. Among authors: moraca f. Nat Commun. 2024 May 29;15(1):4565. doi: 10.1038/s41467-024-49118-y. Nat Commun. 2024. PMID: 38811561 Free PMC article. No abstract available.
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis.
Di Giorgio C, Morretta E, Lupia A, Bellini R, Massa C, Urbani G, Bordoni M, Marchianò S, Lachi G, Rapacciuolo P, Finamore C, Sepe V, Chiara Monti M, Moraca F, Natalizi N, Graziosi L, Distrutti E, Biagioli M, Catalanotti B, Donini A, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: moraca f. Biochem Pharmacol. 2024 May;223:116134. doi: 10.1016/j.bcp.2024.116134. Epub 2024 Mar 15. Biochem Pharmacol. 2024. PMID: 38494064 Free article.
Exploring the DNA2-PNA heterotriplex formation in targeting the Bcl-2 gene promoter: A structural insight by physico-chemical and microsecond-scale MD investigation.
Falanga AP, Lupia A, Tripodi L, Morgillo CM, Moraca F, Roviello GN, Catalanotti B, Amato J, Pastore L, Cerullo V, D'Errico S, Piccialli G, Oliviero G, Borbone N. Falanga AP, et al. Among authors: moraca f. Heliyon. 2024 Jan 22;10(3):e24599. doi: 10.1016/j.heliyon.2024.e24599. eCollection 2024 Feb 15. Heliyon. 2024. PMID: 38317891 Free PMC article.
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer.
Di Giorgio C, Bellini R, Lupia A, Massa C, Urbani G, Bordoni M, Marchianò S, Rosselli R, De Gregorio R, Rapacciuolo P, Sepe V, Morretta E, Monti MC, Moraca F, Cari L, Ullah KRS, Natalizi N, Graziosi L, Distrutti E, Biagioli M, Catalanotti B, Donini A, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: moraca f. Cell Oncol (Dordr). 2024 Apr;47(2):695-710. doi: 10.1007/s13402-023-00893-8. Epub 2023 Nov 9. Cell Oncol (Dordr). 2024. PMID: 37945798 Free PMC article.
Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients.
Gratteri C, Ambrosio FA, Lupia A, Moraca F, Catalanotti B, Costa G, Bellocchi M, Carioti L, Salpini R, Ceccherini-Silberstein F, Frazia S, Malagnino V, Sarmati L, Svicher V, Bryant S, Artese A, Alcaro S. Gratteri C, et al. Among authors: moraca f. Pharmaceuticals (Basel). 2023 Aug 12;16(8):1143. doi: 10.3390/ph16081143. Pharmaceuticals (Basel). 2023. PMID: 37631058 Free PMC article.
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma.
Di Giorgio C, Bellini R, Lupia A, Massa C, Bordoni M, Marchianò S, Rosselli R, Sepe V, Rapacciuolo P, Moraca F, Morretta E, Ricci P, Urbani G, Monti MC, Biagioli M, Distrutti E, Catalanotti B, Zampella A, Fiorucci S. Di Giorgio C, et al. Among authors: moraca f. Front Oncol. 2023 Mar 14;13:1140730. doi: 10.3389/fonc.2023.1140730. eCollection 2023. Front Oncol. 2023. PMID: 36998446 Free PMC article.
Ubiquitylation of BBSome is required for ciliary assembly and signaling.
Chiuso F, Delle Donne R, Giamundo G, Rinaldi L, Borzacchiello D, Moraca F, Intartaglia D, Iannucci R, Senatore E, Lignitto L, Garbi C, Conflitti P, Catalanotti B, Conte I, Feliciello A. Chiuso F, et al. Among authors: moraca f. EMBO Rep. 2023 Apr 5;24(4):e55571. doi: 10.15252/embr.202255571. Epub 2023 Feb 6. EMBO Rep. 2023. PMID: 36744302 Free PMC article.
67 results