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Page 1
Nociceptor-immune interactomes reveal insult-specific immune signatures of pain.
Jain A, Gyori BM, Hakim S, Jain A, Sun L, Petrova V, Bhuiyan SA, Zhen S, Wang Q, Kawaguchi R, Bunga S, Taub DG, Ruiz-Cantero MC, Tong-Li C, Andrews N, Kotoda M, Renthal W, Sorger PK, Woolf CJ. Jain A, et al. Among authors: ruiz cantero mc. Nat Immunol. 2024 Jul;25(7):1296-1305. doi: 10.1038/s41590-024-01857-2. Epub 2024 May 28. Nat Immunol. 2024. PMID: 38806708 Free PMC article.
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds.
Cosentino G, Dichiara M, Ambrosio FA, Leotta CG, Costa G, Procopio F, Costanzo G, Raffa A, Artacho-Cordón A, Ruiz-Cantero MC, Pasquinucci L, Marrazzo A, Pitari GM, Cobos EJ, Alcaro S, Amata E. Cosentino G, et al. Among authors: ruiz cantero mc. Eur J Med Chem. 2025 Jan 5;281:117037. doi: 10.1016/j.ejmech.2024.117037. Epub 2024 Nov 10. Eur J Med Chem. 2025. PMID: 39547082 Free article.
Pharmacological differences in postoperative cutaneous sensitivity, pain at rest, and movement-induced pain in laparotomized mice.
Santos-Caballero M, Hasoun MA, Huerta MÁ, Ruiz-Cantero MC, Tejada MÁ, Robles-Funes M, Fernández-Segura E, Cañizares FJ, González-Cano R, Cobos EJ. Santos-Caballero M, et al. Among authors: ruiz cantero mc. Biomed Pharmacother. 2024 Nov;180:117459. doi: 10.1016/j.biopha.2024.117459. Epub 2024 Sep 20. Biomed Pharmacother. 2024. PMID: 39305815 Free article.
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity.
Dichiara M, Ambrosio FA, Lee SM, Ruiz-Cantero MC, Lombino J, Coricello A, Costa G, Shah D, Costanzo G, Pasquinucci L, Son KN, Cosentino G, González-Cano R, Marrazzo A, Aakalu VK, Cobos EJ, Alcaro S, Amata E. Dichiara M, et al. Among authors: ruiz cantero mc. J Med Chem. 2023 Aug 24;66(16):11447-11463. doi: 10.1021/acs.jmedchem.3c00959. Epub 2023 Aug 3. J Med Chem. 2023. PMID: 37535861 Free PMC article.
Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.
Szczepańska K, Karcz T, Dichiara M, Mogilski S, Kalinowska-Tłuścik J, Pilarski B, Leniak A, Pietruś W, Podlewska S, Popiołek-Barczyk K, Humphrys LJ, Ruiz-Cantero MC, Reiner-Link D, Leitzbach L, Łażewska D, Pockes S, Górka M, Zmysłowski A, Calmels T, Cobos EJ, Marrazzo A, Stark H, Bojarski AJ, Amata E, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: ruiz cantero mc. J Med Chem. 2023 Jul 27;66(14):9658-9683. doi: 10.1021/acs.jmedchem.3c00430. Epub 2023 Jul 7. J Med Chem. 2023. PMID: 37418295 Free PMC article.
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