Sauer F - Search Results

1

XPD stalled on cross-linked DNA provides insight into damage verification.

Kuper J, Hove T, Maidl S, Neitz H, Sauer F, Kempf M, Schroeder T, Greiter E, Höbartner C, Kisker C. Kuper J, et al. Among authors: sauer f. Nat Struct Mol Biol. 2024 Oct;31(10):1580-1588. doi: 10.1038/s41594-024-01323-5. Epub 2024 May 28. Nat Struct Mol Biol. 2024. PMID: 38806694 Free PMC article.

2

In TFIIH, XPD helicase is exclusively devoted to DNA repair.

Kuper J, Braun C, Elias A, Michels G, Sauer F, Schmitt DR, Poterszman A, Egly JM, Kisker C. Kuper J, et al. Among authors: sauer f. PLoS Biol. 2014 Sep 30;12(9):e1001954. doi: 10.1371/journal.pbio.1001954. eCollection 2014 Sep. PLoS Biol. 2014. PMID: 25268380 Free PMC article.

3

Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense.

Fischer A, Harrison KS, Ramirez Y, Auer D, Chowdhury SR, Prusty BK, Sauer F, Dimond Z, Kisker C, Hefty PS, Rudel T. Fischer A, et al. Among authors: sauer f. Elife. 2017 Mar 28;6:e21465. doi: 10.7554/eLife.21465. Elife. 2017. PMID: 28347402 Free PMC article.

4

The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism.

Kaiser S, Sauer F, Kisker C. Kaiser S, et al. Among authors: sauer f. Nat Commun. 2017 Jun 27;8:15907. doi: 10.1038/ncomms15907. Nat Commun. 2017. PMID: 28653661 Free PMC article.

5

Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.

Ramirez YA, Adler TB, Altmann E, Klemm T, Tiesmeyer C, Sauer F, Kathman SG, Statsyuk AV, Sotriffer C, Kisker C. Ramirez YA, et al. Among authors: sauer f. ChemMedChem. 2018 Oct 8;13(19):2014-2023. doi: 10.1002/cmdc.201800364. Epub 2018 Sep 6. ChemMedChem. 2018. PMID: 30028574 Free PMC article.

6

Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities.

Sauer F, Klemm T, Kollampally RB, Tessmer I, Nair RK, Popov N, Kisker C. Sauer F, et al. Mol Cell. 2019 May 2;74(3):421-435.e10. doi: 10.1016/j.molcel.2019.02.029. Epub 2019 Mar 26. Mol Cell. 2019. PMID: 30926243 Free article.

7

Single molecule analysis reveals monomeric XPA bends DNA and undergoes episodic linear diffusion during damage search.

Beckwitt EC, Jang S, Carnaval Detweiler I, Kuper J, Sauer F, Simon N, Bretzler J, Watkins SC, Carell T, Kisker C, Van Houten B. Beckwitt EC, et al. Among authors: sauer f. Nat Commun. 2020 Mar 13;11(1):1356. doi: 10.1038/s41467-020-15168-1. Nat Commun. 2020. PMID: 32170071 Free PMC article.

8

In TFIIH the Arch domain of XPD is mechanistically essential for transcription and DNA repair.

Peissert S, Sauer F, Grabarczyk DB, Braun C, Sander G, Poterszman A, Egly JM, Kuper J, Kisker C. Peissert S, et al. Among authors: sauer f. Nat Commun. 2020 Apr 3;11(1):1667. doi: 10.1038/s41467-020-15241-9. Nat Commun. 2020. PMID: 32245994 Free PMC article.

9

Structural basis for the bi-specificity of USP25 and USP28 inhibitors.

Patzke JV, Sauer F, Nair RK, Endres E, Proschak E, Hernandez-Olmos V, Sotriffer C, Kisker C. Patzke JV, et al. Among authors: sauer f. EMBO Rep. 2024 Jul;25(7):2950-2973. doi: 10.1038/s44319-024-00167-w. Epub 2024 May 30. EMBO Rep. 2024. PMID: 38816515 Free PMC article.

10

Linkage-specific ubiquitin binding interfaces modulate the activity of the chlamydial deubiquitinase Cdu1 towards poly-ubiquitin substrates.

Schlötzer J, Schmalix A, Hügelschäffer S, Rieger D, Sauer F, Tully MD, Rudel T, Wiesner S, Kisker C. Schlötzer J, et al. Among authors: sauer f. PLoS Pathog. 2024 Oct 21;20(10):e1012630. doi: 10.1371/journal.ppat.1012630. eCollection 2024 Oct. PLoS Pathog. 2024. PMID: 39432525 Free PMC article.

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