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Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists.
Kosar M, Sarott RC, Sykes DA, Viray AEG, Vitale RM, Tomašević N, Li X, Ganzoni RLZ, Kicin B, Reichert L, Patej KJ, Gómez-Bouzó U, Guba W, McCormick PJ, Hua T, Gruber CW, Veprintsev DB, Frank JA, Grether U, Carreira EM. Kosar M, et al. Among authors: tomasevic n. ACS Cent Sci. 2024 Mar 11;10(5):956-968. doi: 10.1021/acscentsci.3c01461. eCollection 2024 May 22. ACS Cent Sci. 2024. PMID: 38799662 Free PMC article.
Plant-Derived Cyclotides Modulate κ-Opioid Receptor Signaling.
Muratspahić E, Tomašević N, Nasrollahi-Shirazi S, Gattringer J, Emser FS, Freissmuth M, Gruber CW. Muratspahić E, et al. Among authors: tomasevic n. J Nat Prod. 2021 Aug 27;84(8):2238-2248. doi: 10.1021/acs.jnatprod.1c00301. Epub 2021 Jul 26. J Nat Prod. 2021. PMID: 34308635 Free PMC article.
Chemical synthesis of grafted cyclotides using a "plug and play" approach.
Koehbach J, Muratspahić E, Ahmed ZM, White AM, Tomašević N, Durek T, Clark RJ, Gruber CW, Craik DJ. Koehbach J, et al. Among authors: tomasevic n. RSC Chem Biol. 2024 Apr 29;5(6):567-571. doi: 10.1039/d4cb00008k. eCollection 2024 Jun 5. RSC Chem Biol. 2024. PMID: 38846076 Free PMC article.
Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain.
Muratspahić E, Tomašević N, Koehbach J, Duerrauer L, Hadžić S, Castro J, Schober G, Sideromenos S, Clark RJ, Brierley SM, Craik DJ, Gruber CW. Muratspahić E, et al. Among authors: tomasevic n. J Med Chem. 2021 Jul 8;64(13):9042-9055. doi: 10.1021/acs.jmedchem.1c00158. Epub 2021 Jun 23. J Med Chem. 2021. PMID: 34162205 Free PMC article.
Design, synthesis, conformational analysis, and biological activity of Cα1-to-Cα6 1,4- and 4,1-disubstituted 1H-[1,2,3]triazol-1-yl-bridged oxytocin analogues.
Nuti F, Larregola M, Staśkiewicz A, Retzl B, Tomašević N, Macchia L, Street ME, Jewgiński M, Lequin O, Latajka R, Rovero P, Gruber CW, Chorev M, Papini AM. Nuti F, et al. Among authors: tomasevic n. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2254019. doi: 10.1080/14756366.2023.2254019. Epub 2023 Sep 21. J Enzyme Inhib Med Chem. 2023. PMID: 37735942 Free PMC article.
Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor.
Muratspahić E, Deibler K, Han J, Tomašević N, Jadhav KB, Olivé-Marti AL, Hochrainer N, Hellinger R, Koehbach J, Fay JF, Rahman MH, Hegazy L, Craven TW, Varga BR, Bhardwaj G, Appourchaux K, Majumdar S, Muttenthaler M, Hosseinzadeh P, Craik DJ, Spetea M, Che T, Baker D, Gruber CW. Muratspahić E, et al. Among authors: tomasevic n. Nat Commun. 2023 Dec 6;14(1):8064. doi: 10.1038/s41467-023-43718-w. Nat Commun. 2023. PMID: 38052802 Free PMC article.
CD94+ natural killer cells potentiate pulmonary ischaemia-reperfusion injury.
Tsao T, Qiu L, Bharti R, Shemesh A, Hernandez AM, Cleary SJ, Greenland NY, Santos J, Shi R, Bai L, Richardson J, Dilley K, Will M, Tomasevic N, Sputova T, Salles A, Kang J, Zhang D, Hays SR, Kukreja J, Singer JP, Lanier LL, Looney MR, Greenland JR, Calabrese DR. Tsao T, et al. Among authors: tomasevic n. Eur Respir J. 2024 Sep 26;64(3):2302171. doi: 10.1183/13993003.02171-2023. Print 2024 Sep. Eur Respir J. 2024. PMID: 39190789
46 results