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Pro-inflammatory macrophage activation does not require inhibition of mitochondrial respiration.
Ball AB, Jones AE, Nguyễn KB, Rios A, Marx N, Hsieh WY, Yang K, Desousa BR, Kim KKO, Veliova M, Del Mundo ZM, Shirihai OS, Benincá C, Stiles L, Bensinger SJ, Divakaruni AS. Ball AB, et al. Among authors: beninca c. bioRxiv [Preprint]. 2024 May 14:2024.05.10.593451. doi: 10.1101/2024.05.10.593451. bioRxiv. 2024. Update in: EMBO Rep. 2025 Jan 3. doi: 10.1038/s44319-024-00351-y PMID: 38798678 Free PMC article. Updated. Preprint.
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.
Acin-Perez R, Benincá C, Fernandez Del Rio L, Shu C, Baghdasarian S, Zanette V, Gerle C, Jiko C, Khairallah R, Khan S, Rincon Fernandez Pacheco D, Shabane B, Erion K, Masand R, Dugar S, Ghenoiu C, Schreiner G, Stiles L, Liesa M, Shirihai OS. Acin-Perez R, et al. Among authors: beninca c. EMBO J. 2023 May 15;42(10):e111699. doi: 10.15252/embj.2022111699. Epub 2023 Mar 13. EMBO J. 2023. PMID: 36912136 Free PMC article.
A mammalian-specific Alex3/Gαq protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival.
Izquierdo-Villalba I, Mirra S, Manso Y, Parcerisas A, Rubio J, Del Valle J, Gil-Bea FJ, Ulloa F, Herrero-Lorenzo M, Verdaguer E, Benincá C, Castro-Torres RD, Rebollo E, Marfany G, Auladell C, Navarro X, Enríquez JA, López de Munain A, Soriano E, Aragay AM. Izquierdo-Villalba I, et al. Among authors: beninca c. Sci Signal. 2024 Feb 6;17(822):eabq1007. doi: 10.1126/scisignal.abq1007. Epub 2024 Feb 6. Sci Signal. 2024. PMID: 38320000
The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis.
Acevedo A, Jones AE, Danna BT, Turner R, Montales KP, Benincá C, Reue K, Shirihai OS, Stiles L, Wallace M, Wang Y, Bertholet AM, Divakaruni AS. Acevedo A, et al. Among authors: beninca c. bioRxiv [Preprint]. 2023 Aug 16:2023.08.15.553413. doi: 10.1101/2023.08.15.553413. bioRxiv. 2023. Update in: J Biol Chem. 2024 Mar;300(3):105702. doi: 10.1016/j.jbc.2024.105702 PMID: 37645724 Free PMC article. Updated. Preprint.
NDUFV1 mutations in complex I deficiency: Case reports and review of symptoms.
Zanette V, Valle DD, Telles BA, Robinson AJ, Monteiro V, Santos MLSF, Souza RLR, Benincá C. Zanette V, et al. Among authors: beninca c. Genet Mol Biol. 2021 Nov 19;44(4):e20210149. doi: 10.1590/1678-4685-GMB-2021-0149. eCollection 2021. Genet Mol Biol. 2021. PMID: 34807224 Free PMC article.
28 results