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Sex affects transcriptional associations with schizophrenia across the dorsolateral prefrontal cortex, hippocampus, and caudate nucleus.
Benjamin KJM, Arora R, Feltrin AS, Pertea G, Giles HH, Stolz JM, D'Ignazio L, Collado-Torres L, Shin JH, Ulrich WS, Hyde TM, Kleinman JE, Weinberger DR, Paquola ACM, Erwin JA. Benjamin KJM, et al. Among authors: paquola acm. Nat Commun. 2024 May 10;15(1):3980. doi: 10.1038/s41467-024-48048-z. Nat Commun. 2024. PMID: 38730231 Free PMC article.
Human archetypal pluripotent stem cells differentiate into trophoblast stem cells via endogenous BMP5/7 induction without transitioning through naive state.
Tietze E, Barbosa AR, Araujo B, Euclydes V, Spiegelberg B, Cho HJ, Lee YK, Wang Y, McCord A, Lorenzetti A, Feltrin A, van de Leemput J, Di Carlo P, Ursini G, Benjamin KJ, Brentani H, Kleinman JE, Hyde TM, Weinberger DR, McKay R, Shin JH, Sawada T, Paquola ACM, Erwin JA. Tietze E, et al. Among authors: paquola acm. Sci Rep. 2024 Feb 8;14(1):3291. doi: 10.1038/s41598-024-53381-w. Sci Rep. 2024. PMID: 38332235 Free PMC article.
Analysis of gene expression in the postmortem brain of neurotypical Black Americans reveals contributions of genetic ancestry.
Benjamin KJM, Chen Q, Eagles NJ, Huuki-Myers LA, Collado-Torres L, Stolz JM, Pertea G, Shin JH, Paquola ACM, Hyde TM, Kleinman JE, Jaffe AE, Han S, Weinberger DR. Benjamin KJM, et al. Among authors: paquola acm. Nat Neurosci. 2024 Jun;27(6):1064-1074. doi: 10.1038/s41593-024-01636-0. Epub 2024 May 20. Nat Neurosci. 2024. PMID: 38769152 Free PMC article.
Recapitulation of Perturbed Striatal Gene Expression Dynamics of Donors' Brains With Ventral Forebrain Organoids Derived From the Same Individuals With Schizophrenia.
Sawada T, Barbosa AR, Araujo B, McCord AE, D'Ignazio L, Benjamin KJM, Sheehan B, Zabolocki M, Feltrin A, Arora R, Brandtjen AC, Kleinman JE, Hyde TM, Bardy C, Weinberger DR, Paquola ACM, Erwin JA. Sawada T, et al. Among authors: paquola acm. Am J Psychiatry. 2024 Jun 1;181(6):493-511. doi: 10.1176/appi.ajp.20220723. Epub 2023 Nov 2. Am J Psychiatry. 2024. PMID: 37915216 Free PMC article.
dRFEtools: dynamic recursive feature elimination for omics.
Benjamin KJM, Katipalli T, Paquola ACM. Benjamin KJM, et al. Among authors: paquola acm. Bioinformatics. 2023 Aug 1;39(8):btad513. doi: 10.1093/bioinformatics/btad513. Bioinformatics. 2023. PMID: 37632789 Free PMC article.
Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes.
Benjamin KJM, Chen Q, Jaffe AE, Stolz JM, Collado-Torres L, Huuki-Myers LA, Burke EE, Arora R, Feltrin AS, Barbosa AR, Radulescu E, Pergola G, Shin JH, Ulrich WS, Deep-Soboslay A, Tao R; BrainSeq Consortium; Hyde TM, Kleinman JE, Erwin JA, Weinberger DR, Paquola ACM. Benjamin KJM, et al. Among authors: paquola acm. Nat Neurosci. 2022 Nov;25(11):1559-1568. doi: 10.1038/s41593-022-01182-7. Epub 2022 Nov 1. Nat Neurosci. 2022. PMID: 36319771 Free PMC article.
Variation in TAF1 expression in female carrier induced pluripotent stem cells and human brain ontogeny has implications for adult neostriatum vulnerability in X-linked Dystonia Parkinsonism.
D'Ignazio L, Jacomini RS, Qamar B, Benjamin KJM, Arora R, Sawada T, Evans TA, Diffenderfer KE, Pankonin AR, Hendriks WT, Hyde TM, Kleinman JE, Weinberger DR, Bragg DC, Paquola ACM, Erwin JA. D'Ignazio L, et al. Among authors: paquola acm. eNeuro. 2022 Jul 21;9(4):ENEURO.0129-22.2022. doi: 10.1523/ENEURO.0129-22.2022. Online ahead of print. eNeuro. 2022. PMID: 35868859 Free PMC article.
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients.
Mertens J, Herdy JR, Traxler L, Schafer ST, Schlachetzki JCM, Böhnke L, Reid DA, Lee H, Zangwill D, Fernandes DP, Agarwal RK, Lucciola R, Zhou-Yang L, Karbacher L, Edenhofer F, Stern S, Horvath S, Paquola ACM, Glass CK, Yuan SH, Ku M, Szücs A, Goldstein LSB, Galasko D, Gage FH. Mertens J, et al. Among authors: paquola acm. Cell Stem Cell. 2021 Sep 2;28(9):1533-1548.e6. doi: 10.1016/j.stem.2021.04.004. Epub 2021 Apr 27. Cell Stem Cell. 2021. PMID: 33910058 Free PMC article.
38 results