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The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.
Álvarez L, Haubrich K, Iselin L, Gillioz L, Ruscica V, Lapouge K, Augsten S, Huppertz I, Choudhury NR, Simon B, Masiewicz P, Lethier M, Cusack S, Rittinger K, Gabel F, Leitner A, Michlewski G, Hentze MW, Allain FHT, Castello A, Hennig J. Álvarez L, et al. Among authors: gabel f. Nat Commun. 2024 Oct 1;15(1):8485. doi: 10.1038/s41467-024-52918-x. Nat Commun. 2024. PMID: 39353916 Free PMC article.
Unveiling the crystal structure of thermostable dienelactone hydrolase exhibiting activity on terephthalate esters.
Almeida DV, Ciancaglini I, Sandano ALH, Roman EKB, Andrade VB, Nunes AB, Tramontina R, da Silva VM, Gabel F, Corrêa TLR, Damasio A, Muniz JRC, Squina FM, Garcia W. Almeida DV, et al. Among authors: gabel f. Enzyme Microb Technol. 2024 Oct;180:110498. doi: 10.1016/j.enzmictec.2024.110498. Epub 2024 Aug 21. Enzyme Microb Technol. 2024. PMID: 39182429
A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death.
Mannion J, Gifford V, Bellenie B, Fernando W, Ramos Garcia L, Wilson R, John SW, Udainiya S, Patin EC, Tiu C, Smith A, Goicoechea M, Craxton A, Moraes de Vasconcelos N, Guppy N, Cheung KJ, Cundy NJ, Pierrat O, Brennan A, Roumeliotis TI, Benstead-Hume G, Alexander J, Muirhead G, Layzell S, Lyu W, Roulstone V, Allen M, Baldock H, Legrand A, Gabel F, Serrano-Aparicio N, Starling C, Guo H, Upton J, Gyrd-Hansen M, MacFarlane M, Seddon B, Raynaud F, Roxanis I, Harrington K, Haider S, Choudhary JS, Hoelder S, Tenev T, Meier P. Mannion J, et al. Among authors: gabel f. Immunity. 2024 Jul 9;57(7):1514-1532.e15. doi: 10.1016/j.immuni.2024.04.025. Epub 2024 May 23. Immunity. 2024. PMID: 38788712 Free article.
Structured feedback and operative video debriefing with critical view of safety annotation in training of laparoscopic cholecystectomy: a randomized controlled study.
Cizmic A, Häberle F, Wise PA, Müller F, Gabel F, Mascagni P, Namazi B, Wagner M, Hashimoto DA, Madani A, Alseidi A, Hackert T, Müller-Stich BP, Nickel F. Cizmic A, et al. Among authors: gabel f. Surg Endosc. 2024 Jun;38(6):3241-3252. doi: 10.1007/s00464-024-10843-6. Epub 2024 Apr 23. Surg Endosc. 2024. PMID: 38653899 Free PMC article. Clinical Trial.
Telestration with augmented reality improves the performance of the first ten ex vivo porcine laparoscopic cholecystectomies: a randomized controlled study.
Cizmic A, Müller F, Wise PA, Häberle F, Gabel F, Kowalewski KF, Bintintan V, Müller-Stich BP, Nickel F. Cizmic A, et al. Among authors: gabel f. Surg Endosc. 2023 Oct;37(10):7839-7848. doi: 10.1007/s00464-023-10360-y. Epub 2023 Aug 23. Surg Endosc. 2023. PMID: 37612445 Free PMC article. Clinical Trial.
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