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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death.
Mannion J, Gifford V, Bellenie B, Fernando W, Ramos Garcia L, Wilson R, John SW, Udainiya S, Patin EC, Tiu C, Smith A, Goicoechea M, Craxton A, Moraes de Vasconcelos N, Guppy N, Cheung KJ, Cundy NJ, Pierrat O, Brennan A, Roumeliotis TI, Benstead-Hume G, Alexander J, Muirhead G, Layzell S, Lyu W, Roulstone V, Allen M, Baldock H, Legrand A, Gabel F, Serrano-Aparicio N, Starling C, Guo H, Upton J, Gyrd-Hansen M, MacFarlane M, Seddon B, Raynaud F, Roxanis I, Harrington K, Haider S, Choudhary JS, Hoelder S, Tenev T, Meier P. Mannion J, et al. Among authors: brennan a. Immunity. 2024 Jul 9;57(7):1514-1532.e15. doi: 10.1016/j.immuni.2024.04.025. Epub 2024 May 23. Immunity. 2024. PMID: 38788712 Free article.
Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones.
Harnden AC, Davis OA, Box GM, Hayes A, Johnson LD, Henley AT, de Haven Brandon AK, Valenti M, Cheung KJ, Brennan A, Huckvale R, Pierrat OA, Talbot R, Bright MD, Akpinar HA, Miller DSJ, Tarantino D, Gowan S, de Klerk S, McAndrew PC, Le Bihan YV, Meniconi M, Burke R, Kirkin V, van Montfort RLM, Raynaud FI, Rossanese OW, Bellenie BR, Hoelder S. Harnden AC, et al. Among authors: brennan a. J Med Chem. 2023 Apr 27;66(8):5892-5906. doi: 10.1021/acs.jmedchem.3c00155. Epub 2023 Apr 7. J Med Chem. 2023. PMID: 37026591 Free PMC article.
Prevalence and progression of chronic kidney disease among adults undergoing creatinine testing in South African public healthcare facilities: a study leveraging data from South Africa's National Health Laboratory Service (NHLS).
Brennan AT, Kileel EM, Khoza S, Crowther NJ, Bor J, Fox MP, Rosen S, Hibberd P, Raal F, Chetty K, Mlisana K, George JA. Brennan AT, et al. BMJ Public Health. 2024 Jul;2(1):e000799. doi: 10.1136/bmjph-2023-000799. Epub 2024 Jul 30. BMJ Public Health. 2024. PMID: 39698394 Free PMC article.
Comprehensive characterization of European house dust contaminants: Concentrations and profiles, geographical variability, and implications for chemical regulation and health risk.
Haglund P, Alygizakis NA, Covaci A, Melymuk L, Nizzetto PB, Rostkowski P, Albinet A, Alirai S, Aurich D, Bieber S, Ballesteros-Gómez A, Brennan AA, Budzinski H, Castro G, den Ouden F, Dévier MH, Dulio V, Feng YL, Gabriel M, Gallampois C, García-Vara M, Giovanoulis G, Harrad S, Jacobs G, Jobst KJ, Kaserzon S, Kumirska J, Lestremau F, Lambropoulou D, Letzel T, de Alda ML, Nipen M, Oswald P, Poma G, Přibylová P, Price EJ, Raffy G, Schulze B, Schymanski EL, Šenk P, Wei S, Slobodnik J, Andújar BT, Täubel M, Thomaidis NS, Wang T, Wang X. Haglund P, et al. Among authors: brennan aa. Sci Total Environ. 2024 Dec 20;957:177639. doi: 10.1016/j.scitotenv.2024.177639. Epub 2024 Dec 2. Sci Total Environ. 2024. PMID: 39626414
Understanding long-term risk in Percutaneous Coronary Intervention (PCI) in the Australian contemporary era with a focus on defining Complex Revascularisation in High-Risk Indicated Patients (CHIP).
Yeoh J, Hamilton GW, Dinh D, Brennan A, Reid CM, Stub D, Freeman M, Sebastian M, Oqueli E, Ajani A, Scully T, Toner L, Picardo S, Horrigan M, Yudi MB, Farouque O, Seevanayagam S, Clark DJ; Melbourne Interventional Group. Yeoh J, et al. Among authors: brennan a. Cardiovasc Revasc Med. 2024 Nov 8:S1553-8389(24)00714-0. doi: 10.1016/j.carrev.2024.11.001. Online ahead of print. Cardiovasc Revasc Med. 2024. PMID: 39532593
1,306 results