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A new class of 7-deazaguanine agents targeting autoimmune diseases: dramatic reduction of synovial fibroblast IL-6 production from human rheumatoid arthritis patients and improved performance against murine experimental autoimmune encephalomyelitis.
Cotter M, Quinn SM, Fearon U, Ansboro S, Rakovic T, Southern JM, Kelly VP, Connon SJ. Cotter M, et al. Among authors: rakovic t. RSC Med Chem. 2024 Mar 28;15(5):1556-1564. doi: 10.1039/d4md00028e. eCollection 2024 May 22. RSC Med Chem. 2024. PMID: 38784475 Free PMC article.