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OpenSAFELY: A platform for analysing electronic health records designed for reproducible research.
Nab L, Schaffer AL, Hulme W, DeVito NJ, Dillingham I, Wiedemann M, Andrews CD, Curtis H, Fisher L, Green A, Massey J, Walters CE, Higgins R, Cunningham C, Morley J, Mehrkar A, Hart L, Davy S, Evans D, Hickman G, Inglesby P, Morton CE, Smith RM, Ward T, O'Dwyer T, Maude S, Bridges L, Butler-Cole BFC, Stables CL, Stokes P, Bates C, Cockburn J, Hester F, Parry J, Bhaskaran K, Schultze A, Rentsch CT, Mathur R, Tomlinson LA, Williamson EJ, Smeeth L, Walker A, Bacon S, MacKenna B, Goldacre B. Nab L, et al. Among authors: higgins r. Pharmacoepidemiol Drug Saf. 2024 Jun;33(6):e5815. doi: 10.1002/pds.5815. Pharmacoepidemiol Drug Saf. 2024. PMID: 38783412 Free PMC article.
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY.
Green ACA, Curtis HJ, Higgins R, Nab L, Mahalingasivam V, Smith RM, Mehrkar A, Inglesby P, Drysdale H, DeVito NJ, Croker R, Rentsch CT, Bhaskaran K, Tazare J, Zheng B, Andrews CD, Bacon SCJ, Davy S, Dillingham I, Evans D, Fisher L, Hickman G, Hopcroft LEM, Hulme WJ, Massey J, MacDonald O, Morley J, Morton CE, Park RY, Walker AJ, Ward T, Wiedemann M, Bates C, Cockburn J, Parry J, Hester F, Harper S, Douglas IJ, Evans SJW, Goldacre B, Tomlinson LA, MacKenna B. Green ACA, et al. Among authors: higgins r. BMJ Med. 2023 Jan 13;2(1):e000276. doi: 10.1136/bmjmed-2022-000276. eCollection 2023. BMJ Med. 2023. PMID: 36936265 Free PMC article.
Ethnic differences in the indirect effects of the COVID-19 pandemic on clinical monitoring and hospitalisations for non-COVID conditions in England: a population-based, observational cohort study using the OpenSAFELY platform.
Costello RE, Tazare J, Piehlmaier D, Herrett E, Parker EPK, Zheng B, Mansfield KE, Henderson AD, Carreira H, Bidulka P, Wong AYS, Warren-Gash C, Hayes JF, Quint JK, MacKenna B, Mehrkar A, Eggo RM, Katikireddi SV, Tomlinson L, Langan SM, Mathur R; LH&W NCS (or CONVALESCENCE) Collaborative; OpenSAFELY collaborative. Costello RE, et al. EClinicalMedicine. 2023 Jun 29;61:102077. doi: 10.1016/j.eclinm.2023.102077. eCollection 2023 Jul. EClinicalMedicine. 2023. PMID: 37434746 Free PMC article.
Eleven key measures for monitoring general practice clinical activity during COVID-19: A retrospective cohort study using 48 million adults' primary care records in England through OpenSAFELY.
Fisher L, Curtis HJ, Croker R, Wiedemann M, Speed V, Wood C, Brown A, Hopcroft LEM, Higgins R, Massey J, Inglesby P, Morton CE, Walker AJ, Morley J, Mehrkar A, Bacon S, Hickman G, Macdonald O, Lewis T, Wood M, Myers M, Samuel M, Conibere R, Baqir W, Sood H, Drury C, Collison K, Bates C, Evans D, Dillingham I, Ward T, Davy S, Smith RM, Hulme W, Green A, Parry J, Hester F, Harper S, Cockburn J, O'Hanlon S, Eavis A, Jarvis R, Avramov D, Griffiths P, Fowles A, Parkes N, MacKenna B, Goldacre B. Fisher L, et al. Among authors: higgins r. Elife. 2023 Jul 27;12:e84673. doi: 10.7554/eLife.84673. Elife. 2023. PMID: 37498081 Free PMC article.
Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic: an efficient cluster randomised controlled trial using the OpenSAFELY platform.
Ainsworth B, Horwood J, Walter SR, Miller S, Chalder M, De Vocht F, Denison-Day J, Elwenspoek MMC, Curtis HJ, Bates C, Mehrkar A, Bacon S, Goldacre B; OpenSAFELY Collaborative; Craggs P, Amlôt R, Francis N, Little P, Macleod J, Moore M, Morton K, Rice C, Sterne J, Stuart B, Towler L, Willcox ML, Yardley L. Ainsworth B, et al. Implement Sci. 2023 Dec 4;18(1):67. doi: 10.1186/s13012-023-01321-z. Implement Sci. 2023. PMID: 38049846 Free PMC article. Clinical Trial.
Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic: a national case-control and cohort study.
Zhong X, Ashiru-Oredope D, Pate A, Martin GP, Sharma A, Dark P, Felton T, Lake C, MacKenna B, Mehrkar A, Bacon SCJ, Massey J, Inglesby P, Goldacre B; OpenSAFELY Collaborative; Hand K, Bladon S, Cunningham N, Gilham E, Brown CS, Mirfenderesky M, Palin V, van Staa TP. Zhong X, et al. EClinicalMedicine. 2023 Nov 23;66:102321. doi: 10.1016/j.eclinm.2023.102321. eCollection 2023 Dec. EClinicalMedicine. 2023. PMID: 38192590 Free PMC article.
Impact of long COVID on health-related quality-of-life: an OpenSAFELY population cohort study using patient-reported outcome measures (OpenPROMPT).
Carlile O, Briggs A, Henderson AD, Butler-Cole BFC, Tazare J, Tomlinson LA, Marks M, Jit M, Lin LY, Bates C, Parry J, Bacon SCJ, Dillingham I, Dennison WA, Costello RE, Walker AJ, Hulme W, Goldacre B, Mehrkar A, MacKenna B; OpenSAFELY Collaborative; Herrett E, Eggo RM. Carlile O, et al. Lancet Reg Health Eur. 2024 Apr 24;40:100908. doi: 10.1016/j.lanepe.2024.100908. eCollection 2024 May. Lancet Reg Health Eur. 2024. PMID: 38689605 Free PMC article.
Clinical coding of long COVID in primary care 2020-2023 in a cohort of 19 million adults: an OpenSAFELY analysis.
Henderson AD, Butler-Cole BF, Tazare J, Tomlinson LA, Marks M, Jit M, Briggs A, Lin LY, Carlile O, Bates C, Parry J, Bacon SC, Dillingham I, Dennison WA, Costello RE, Wei Y, Walker AJ, Hulme W, Goldacre B, Mehrkar A, MacKenna B; OpenSAFELY Collaborative; Herrett E, Eggo RM. Henderson AD, et al. EClinicalMedicine. 2024 May 17;72:102638. doi: 10.1016/j.eclinm.2024.102638. eCollection 2024 Jun. EClinicalMedicine. 2024. PMID: 38800803 Free PMC article.
Incidence and treatment of group A streptococcal infections during covid-19 pandemic and 2022 outbreak: retrospective cohort study in England using OpenSAFELY-TPP.
Cunningham C, Fisher L, Wood C, Speed V, Brown AD, Curtis H, Higgins R, Croker R, Butler-Cole BF, Evans D, Inglesby P, Dillingham I, Bacon SC, Beech E, Hand K, Davy S, Ward T, Hickman G, Bridges L, O'Dwyer T, Maude S, Smith RM, Mehrkar A, Hart LC, Bates C, Cockburn J, Parry J, Hester F, Harper S, Goldacre B, MacKenna B. Cunningham C, et al. Among authors: higgins r. BMJ Med. 2024 May 24;3(1):e000791. doi: 10.1136/bmjmed-2023-000791. eCollection 2024. BMJ Med. 2024. PMID: 38803829 Free PMC article.
Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY.
Wiedemann M, Speed V, Cunningham C, Higgins R, Curtis HJ, Andrews C, Fisher L, Hopcroft L, Rentsch CT, Mahalingasivam V, Tomlinson L, Morton C, Samuel M, Green A, Wood C, Brown AD, Massey J, Walters C, Smith RM, Inglesby P, Evans D, Maude S, Dillingham I, Walker AJ, Morley J, Mehrkar A, Bacon S, Bates C, Cockburn J, Parry J, Hester F, McManus RJ, Goldacre B, MacKenna B. Wiedemann M, et al. Among authors: higgins r. Open Heart. 2024 Aug 30;11(2):e002732. doi: 10.1136/openhrt-2024-002732. Open Heart. 2024. PMID: 39214534 Free PMC article.
1,710 results