Froese A - Search Results

1

Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation.

Pavlaki N, Froese A, Li W, De Jong KA, Geertz B, Subramanian H, Mohagaonkar S, Luo X, Schubert M, Wiegmann R, Margaria JP, Ghigo A, Kämmerer S, Hirsch E, El-Armouche A, Guan K, Nikolaev VO. Pavlaki N, et al. Among authors: froese a. Cardiovasc Res. 2024 Jul 31;120(9):1011-1023. doi: 10.1093/cvr/cvae094. Cardiovasc Res. 2024. PMID: 38776406

2

Imaging alterations of cardiomyocyte cAMP microdomains in disease.

Froese A, Nikolaev VO. Froese A, et al. Front Pharmacol. 2015 Aug 25;6:172. doi: 10.3389/fphar.2015.00172. eCollection 2015. Front Pharmacol. 2015. PMID: 26379548 Free PMC article. Review.

3

Heart failure leads to altered β2-adrenoceptor/cyclic adenosine monophosphate dynamics in the sarcolemmal phospholemman/Na,K ATPase microdomain.

Bastug-Özel Z, Wright PT, Kraft AE, Pavlovic D, Howie J, Froese A, Fuller W, Gorelik J, Shattock MJ, Nikolaev VO. Bastug-Özel Z, et al. Among authors: froese a. Cardiovasc Res. 2019 Mar 1;115(3):546-555. doi: 10.1093/cvr/cvy221. Cardiovasc Res. 2019. PMID: 30165515 Free PMC article.

4

Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains.

Pavlaki N, De Jong KA, Geertz B, Nikolaev VO, Froese A. Pavlaki N, et al. Among authors: froese a. Cells. 2021 Mar 3;10(3):535. doi: 10.3390/cells10030535. Cells. 2021. PMID: 33802377 Free PMC article.

5

CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors.

Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW. Manfra O, et al. Among authors: froese a. Cardiovasc Res. 2022 May 6;118(6):1506-1519. doi: 10.1093/cvr/cvab167. Cardiovasc Res. 2022. PMID: 33970224 Free PMC article.

6

CRISPR/Cas9 Knock-Out in Primary Neonatal and Adult Cardiomyocytes Reveals Distinct cAMP Dynamics Regulation by Various PDE2A and PDE3A Isoforms.

Skryabin EB, De Jong KA, Subramanian H, Bork NI, Froese A, Skryabin BV, Nikolaev VO. Skryabin EB, et al. Among authors: froese a. Cells. 2023 Jun 4;12(11):1543. doi: 10.3390/cells12111543. Cells. 2023. PMID: 37296663 Free PMC article.

7

Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP.

Subramanian H, Froese A, Jönsson P, Schmidt H, Gorelik J, Nikolaev VO. Subramanian H, et al. Among authors: froese a. Nat Commun. 2018 Jun 22;9(1):2446. doi: 10.1038/s41467-018-04891-5. Nat Commun. 2018. PMID: 29934640 Free PMC article.

8

Calcineurin Aβ-Specific Anchoring Confers Isoform-Specific Compartmentation and Function in Pathological Cardiac Myocyte Hypertrophy.

Li X, Li J, Martinez EC, Froese A, Passariello CL, Henshaw K, Rusconi F, Li Y, Yu Q, Thakur H, Nikolaev VO, Kapiloff MS. Li X, et al. Among authors: froese a. Circulation. 2020 Sep 8;142(10):948-962. doi: 10.1161/CIRCULATIONAHA.119.044893. Epub 2020 Jul 2. Circulation. 2020. PMID: 32611257 Free PMC article.

9

Internalized Receptor for Glucose-dependent Insulinotropic Peptide stimulates adenylyl cyclase on early endosomes.

Ismail S, Gherardi MJ, Froese A, Zanoun M, Gigoux V, Clerc P, Gaits-Iacovoni F, Steyaert J, Nikolaev VO, Fourmy D. Ismail S, et al. Among authors: froese a. Biochem Pharmacol. 2016 Nov 15;120:33-45. doi: 10.1016/j.bcp.2016.09.009. Epub 2016 Sep 15. Biochem Pharmacol. 2016. PMID: 27641811

10

Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs As Novel Tools for Non-Invasive Cell Assays.

Ruthenbeck A, Marangoni E, Diercks BP, Krüger A, Froese A, Bork NI, Nikolaev VO, Guse AH, Meier C. Ruthenbeck A, et al. Among authors: froese a. Molecules. 2018 Nov 13;23(11):2960. doi: 10.3390/molecules23112960. Molecules. 2018. PMID: 30428589 Free PMC article.

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