De Jong KA - Search Results

1

Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation.

Pavlaki N, Froese A, Li W, De Jong KA, Geertz B, Subramanian H, Mohagaonkar S, Luo X, Schubert M, Wiegmann R, Margaria JP, Ghigo A, Kämmerer S, Hirsch E, El-Armouche A, Guan K, Nikolaev VO. Pavlaki N, et al. Among authors: de jong ka. Cardiovasc Res. 2024 Jul 31;120(9):1011-1023. doi: 10.1093/cvr/cvae094. Cardiovasc Res. 2024. PMID: 38776406

2

Remodelling of cAMP dynamics within the SERCA2a microdomain in heart failure with preserved ejection fraction caused by obesity and type 2 diabetes.

Lai P, Hille SS, Subramanian H, Wiegmann R, Roser P, Müller OJ, Nikolaev VO, De Jong KA. Lai P, et al. Among authors: de jong ka. Cardiovasc Res. 2024 Mar 14;120(3):273-285. doi: 10.1093/cvr/cvad178. Cardiovasc Res. 2024. PMID: 38099489 Free PMC article.

3

Multifaceted remodelling of cAMP microdomains driven by different aetiologies of heart failure.

De Jong KA, Nikolaev VO. De Jong KA, et al. FEBS J. 2021 Dec;288(23):6603-6622. doi: 10.1111/febs.15706. Epub 2021 Jan 23. FEBS J. 2021. PMID: 33415835 Free article. Review.

4

Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains.

Pavlaki N, De Jong KA, Geertz B, Nikolaev VO, Froese A. Pavlaki N, et al. Among authors: de jong ka. Cells. 2021 Mar 3;10(3):535. doi: 10.3390/cells10030535. Cells. 2021. PMID: 33802377 Free PMC article.

5

Understanding the Role of SERCA2a Microdomain Remodeling in Heart Failure Induced by Obesity and Type 2 Diabetes.

Lai P, Nikolaev VO, De Jong KA. Lai P, et al. Among authors: de jong ka. J Cardiovasc Dev Dis. 2022 May 19;9(5):163. doi: 10.3390/jcdd9050163. J Cardiovasc Dev Dis. 2022. PMID: 35621874 Free PMC article. Review.

6

CRISPR/Cas9 Knock-Out in Primary Neonatal and Adult Cardiomyocytes Reveals Distinct cAMP Dynamics Regulation by Various PDE2A and PDE3A Isoforms.

Skryabin EB, De Jong KA, Subramanian H, Bork NI, Froese A, Skryabin BV, Nikolaev VO. Skryabin EB, et al. Among authors: de jong ka. Cells. 2023 Jun 4;12(11):1543. doi: 10.3390/cells12111543. Cells. 2023. PMID: 37296663 Free PMC article.

7

The role of compartmentalized β-AR/cAMP signaling in the regulation of lipolysis in white and brown adipocytes.

De Jong KA, Siddig S, Pfeifer A, Nikolaev VO. De Jong KA, et al. FEBS J. 2024 May 15. doi: 10.1111/febs.17157. Online ahead of print. FEBS J. 2024. PMID: 38747241 Review.

8

Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes.

De Jong KA, Ehret S, Heeren J, Nikolaev VO. De Jong KA, et al. Cell Rep. 2023 May 30;42(5):112433. doi: 10.1016/j.celrep.2023.112433. Epub 2023 Apr 25. Cell Rep. 2023. PMID: 37099421 Free article.

9

Polycystic ovarian syndrome increases prevalence of concentric hypertrophy in normotensive obese women.

De Jong KA, Berisha F, Naderpoor N, Appelbe A, Kotowicz MA, Cukier K, McGee SL, Nikolaev VO. De Jong KA, et al. PLoS One. 2022 Feb 25;17(2):e0263312. doi: 10.1371/journal.pone.0263312. eCollection 2022. PLoS One. 2022. PMID: 35213570 Free PMC article.

10

Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation.

Jungen C, Scherschel K, Flenner F, Jee H, Rajendran P, De Jong KA, Nikolaev V, Meyer C, Ardell JL, Tompkins JD. Jungen C, et al. Among authors: de jong ka. Am J Physiol Heart Circ Physiol. 2019 Dec 1;317(6):H1328-H1341. doi: 10.1152/ajpheart.00249.2019. Epub 2019 Oct 18. Am J Physiol Heart Circ Physiol. 2019. PMID: 31625779 Free PMC article.

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