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Page 1
Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes.
Pekayvaz K, Losert C, Knottenberg V, Gold C, van Blokland IV, Oelen R, Groot HE, Benjamins JW, Brambs S, Kaiser R, Gottschlich A, Hoffmann GV, Eivers L, Martinez-Navarro A, Bruns N, Stiller S, Akgöl S, Yue K, Polewka V, Escaig R, Joppich M, Janjic A, Popp O, Kobold S, Petzold T, Zimmer R, Enard W, Saar K, Mertins P, Huebner N, van der Harst P, Franke LH, van der Wijst MGP, Massberg S, Heinig M, Nicolai L, Stark K. Pekayvaz K, et al. Among authors: heinig m. Nat Med. 2024 Jun;30(6):1696-1710. doi: 10.1038/s41591-024-02953-4. Epub 2024 May 21. Nat Med. 2024. PMID: 38773340 Free PMC article.
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.
Heinig M, Petretto E, Wallace C, Bottolo L, Rotival M, Lu H, Li Y, Sarwar R, Langley SR, Bauerfeind A, Hummel O, Lee YA, Paskas S, Rintisch C, Saar K, Cooper J, Buchan R, Gray EE, Cyster JG; Cardiogenics Consortium; Erdmann J, Hengstenberg C, Maouche S, Ouwehand WH, Rice CM, Samani NJ, Schunkert H, Goodall AH, Schulz H, Roider HG, Vingron M, Blankenberg S, Münzel T, Zeller T, Szymczak S, Ziegler A, Tiret L, Smyth DJ, Pravenec M, Aitman TJ, Cambien F, Clayton D, Todd JA, Hubner N, Cook SA. Heinig M, et al. Nature. 2010 Sep 23;467(7314):460-4. doi: 10.1038/nature09386. Epub 2010 Sep 8. Nature. 2010. PMID: 20827270 Free PMC article.
The single-cell eQTLGen consortium.
van der Wijst M, de Vries DH, Groot HE, Trynka G, Hon CC, Bonder MJ, Stegle O, Nawijn MC, Idaghdour Y, van der Harst P, Ye CJ, Powell J, Theis FJ, Mahfouz A, Heinig M, Franke L. van der Wijst M, et al. Among authors: heinig m. Elife. 2020 Mar 9;9:e52155. doi: 10.7554/eLife.52155. Elife. 2020. PMID: 32149610 Free PMC article.
Cells of the adult human heart.
Litviňuková M, Talavera-López C, Maatz H, Reichart D, Worth CL, Lindberg EL, Kanda M, Polanski K, Heinig M, Lee M, Nadelmann ER, Roberts K, Tuck L, Fasouli ES, DeLaughter DM, McDonough B, Wakimoto H, Gorham JM, Samari S, Mahbubani KT, Saeb-Parsy K, Patone G, Boyle JJ, Zhang H, Zhang H, Viveiros A, Oudit GY, Bayraktar OA, Seidman JG, Seidman CE, Noseda M, Hubner N, Teichmann SA. Litviňuková M, et al. Among authors: heinig m. Nature. 2020 Dec;588(7838):466-472. doi: 10.1038/s41586-020-2797-4. Epub 2020 Sep 24. Nature. 2020. PMID: 32971526 Free PMC article.
Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data.
Li S, Schmid KT, de Vries DH, Korshevniuk M, Losert C, Oelen R, van Blokland IV; BIOS Consortium, sc-eQTLgen Consortium; Groot HE, Swertz MA, van der Harst P, Westra HJ, van der Wijst MGP, Heinig M, Franke L. Li S, et al. Among authors: heinig m. Genome Biol. 2023 Apr 18;24(1):80. doi: 10.1186/s13059-023-02897-x. Genome Biol. 2023. PMID: 37072791 Free PMC article.
Single-Cell Dissection of the Immune Response After Acute Myocardial Infarction.
van Blokland IV, Oelen R, Groot HE, Benjamins JW, Pekayvaz K, Losert C, Knottenberg V, Heinig M, Nicolai L, Stark K, van der Harst P, Franke L, van der Wijst MGP. van Blokland IV, et al. Among authors: heinig m. Circ Genom Precis Med. 2024 Jun;17(3):e004374. doi: 10.1161/CIRCGEN.123.004374. Epub 2024 May 16. Circ Genom Precis Med. 2024. PMID: 38752343 Free PMC article.
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis.
Gaertner F, Ishikawa-Ankerhold H, Stutte S, Fu W, Weitz J, Dueck A, Nelakuditi B, Fumagalli V, van den Heuvel D, Belz L, Sobirova G, Zhang Z, Titova A, Navarro AM, Pekayvaz K, Lorenz M, von Baumgarten L, Kranich J, Straub T, Popper B, Zheden V, Kaufmann WA, Guo C, Piontek G, von Stillfried S, Boor P, Colonna M, Clauß S, Schulz C, Brocker T, Walzog B, Scheiermann C, Aird WC, Nerlov C, Stark K, Petzold T, Engelhardt S, Sixt M, Hauschild R, Rudelius M, Oostendorp RAJ, Iannacone M, Heinig M, Massberg S. Gaertner F, et al. Among authors: heinig m. Nature. 2024 Jul;631(8021):645-653. doi: 10.1038/s41586-024-07671-y. Epub 2024 Jul 10. Nature. 2024. PMID: 38987596 Free PMC article.
Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single-cell resolution.
Caporale N, Castaldi D, Rigoli MT, Cheroni C, Valenti A, Stucchi S, Lessi M, Bulgheresi D, Trattaro S, Pezzali M, Vitriolo A, Lopez-Tobon A, Bonfanti M, Ricca D, Schmid KT, Heinig M, Theis FJ, Villa CE, Testa G. Caporale N, et al. Among authors: heinig m. Nat Methods. 2024 Dec 9. doi: 10.1038/s41592-024-02555-5. Online ahead of print. Nat Methods. 2024. PMID: 39653820
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.
Monti J, Fischer J, Paskas S, Heinig M, Schulz H, Gösele C, Heuser A, Fischer R, Schmidt C, Schirdewan A, Gross V, Hummel O, Maatz H, Patone G, Saar K, Vingron M, Weldon SM, Lindpaintner K, Hammock BD, Rohde K, Dietz R, Cook SA, Schunck WH, Luft FC, Hubner N. Monti J, et al. Among authors: heinig m. Nat Genet. 2008 May;40(5):529-37. doi: 10.1038/ng.129. Nat Genet. 2008. PMID: 18443590 Free PMC article.
SNP and haplotype mapping for genetic analysis in the rat.
STAR Consortium; Saar K, Beck A, Bihoreau MT, Birney E, Brocklebank D, Chen Y, Cuppen E, Demonchy S, Dopazo J, Flicek P, Foglio M, Fujiyama A, Gut IG, Gauguier D, Guigo R, Guryev V, Heinig M, Hummel O, Jahn N, Klages S, Kren V, Kube M, Kuhl H, Kuramoto T, Kuroki Y, Lechner D, Lee YA, Lopez-Bigas N, Lathrop GM, Mashimo T, Medina I, Mott R, Patone G, Perrier-Cornet JA, Platzer M, Pravenec M, Reinhardt R, Sakaki Y, Schilhabel M, Schulz H, Serikawa T, Shikhagaie M, Tatsumoto S, Taudien S, Toyoda A, Voigt B, Zelenika D, Zimdahl H, Hubner N. STAR Consortium, et al. Among authors: heinig m. Nat Genet. 2008 May;40(5):560-6. doi: 10.1038/ng.124. Nat Genet. 2008. PMID: 18443594 Free PMC article.
200 results