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Previously reported CCDC26 risk variant and novel germline variants in GALNT13, AR, and MYO10 associated with familial glioma in Finland.
Nurminen R, Afyounian E, Paunu N, Katainen R, Isomäki M, Nurminen A, Scaravilli M, Tolppanen J, Fey V, Kivinen A, Helén P, Välimäki N, Kesseli J, Aaltonen LA, Haapasalo H, Nykter M, Rautajoki KJ. Nurminen R, et al. Among authors: haapasalo h. Sci Rep. 2024 May 21;14(1):11562. doi: 10.1038/s41598-024-62296-5. Sci Rep. 2024. PMID: 38773237 Free PMC article.
Aberrant DNA methylation distorts developmental trajectories in atypical teratoid/rhabdoid tumors.
Pekkarinen M, Nordfors K, Uusi-Mäkelä J, Kytölä V, Hartewig A, Huhtala L, Rauhala M, Urhonen H, Häyrynen S, Afyounian E, Yli-Harja O, Zhang W, Helen P, Lohi O, Haapasalo H, Haapasalo J, Nykter M, Kesseli J, Rautajoki KJ. Pekkarinen M, et al. Among authors: haapasalo h. Life Sci Alliance. 2024 Mar 18;7(6):e202302088. doi: 10.26508/lsa.202302088. Print 2024 Jun. Life Sci Alliance. 2024. PMID: 38499326 Free PMC article.
Protumoral lipid droplet-loaded macrophages are enriched in human glioblastoma and can be therapeutically targeted.
Governa V, de Oliveira KG, Bång-Rudenstam A, Offer S, Cerezo-Magaña M, Li J, Beyer S, Johansson MC, Månsson AS, Edvardsson C, Durmo F, Gustafsson E, Boukredine A, Jeannot P, Schmidt K, Gezelius E, Menard JA, Garza R, Jakobsson J, de Neergaard T, Sundgren PC, Tiihonen AM, Haapasalo H, Rautajoki KJ, Nordenfelt P, Darabi A, Forsberg-Nilsson K, Pietras A, Talbot H, Bengzon J, Belting M. Governa V, et al. Among authors: haapasalo h. Sci Transl Med. 2024 Oct 30;16(771):eadk1168. doi: 10.1126/scitranslmed.adk1168. Epub 2024 Oct 30. Sci Transl Med. 2024. PMID: 39475570
Patient-derived glioma organoids real time identification of IDH mutation, 1p/19q-codeletion and CDKN2A/B homozygous deletion with differential ion mobility spectrometry.
Hermelo I, Haapala I, Mäkelä M, Jacome Sanz D, Kontunen A, Karjalainen M, Müller P, Lehtimäki K, Nykter M, Frösén J, Haapasalo H, Roine A, Oksala N, Nordfors K, Vehkaoja A, Haapasalo J. Hermelo I, et al. Among authors: haapasalo h. J Neurooncol. 2025 Feb;171(3):691-703. doi: 10.1007/s11060-024-04891-0. Epub 2024 Nov 23. J Neurooncol. 2025. PMID: 39578301 Free PMC article.
Unsupervised clustering reveals noncanonical myeloid cell subsets in the brain tumor microenvironment.
Hermelo I, Virtanen T, Salonen I, Nätkin R, Keitaanniemi S, Tiihonen AM, Lehtipuro S, Kummola L, Raulamo E, Nordfors K, Haapasalo H, Rauhala M, Kesseli J, Nykter M, Haapasalo J, Rautajoki K. Hermelo I, et al. Among authors: haapasalo h. Cancer Immunol Immunother. 2025 Jan 3;74(2):63. doi: 10.1007/s00262-024-03920-1. Cancer Immunol Immunother. 2025. PMID: 39751910 Free PMC article.
Rapid identification of pediatric brain tumors with differential mobility spectrometry.
Haapala I, Rauhameri A, Mäkelä M, Karjalainen M, Kontunen A, Mieskolainen M, Haapasalo H, Roine A, Oksala N, Vehkaoja A, Haapasalo J, Nordfors K. Haapala I, et al. Among authors: haapasalo h. Front Oncol. 2024 Apr 30;14:1352509. doi: 10.3389/fonc.2024.1352509. eCollection 2024. Front Oncol. 2024. PMID: 38746683 Free PMC article.
Differentiation of highly pathogenic strains of human JC polyomavirus in neurological patients by next generation sequencing.
Auvinen E, Honkimaa A, Laine P, Passerini S, Moens U, Pietropaolo V, Saarela M, Maunula L, Mannonen L, Tynninen O, Haapasalo H, Rauramaa T, Auvinen P, Liimatainen H. Auvinen E, et al. Among authors: haapasalo h. J Clin Virol. 2024 Apr;171:105652. doi: 10.1016/j.jcv.2024.105652. Epub 2024 Feb 12. J Clin Virol. 2024. PMID: 38364704 Free article.
221 results