Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.
Martinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF.
Martinez HA, et al. Among authors: bollyky pl.
Nat Commun. 2024 Feb 20;15(1):1564. doi: 10.1038/s41467-024-45012-9.
Nat Commun. 2024.
PMID: 38378682
Free PMC article.