Koirala B - Search Results

1

Cinnamosyn, a Cinnamoylated Synthetic-Bioinformatic Natural Product with Cytotoxic Activity.

MacIntyre LW, Koirala B, Rosenzweig A, Morales-Amador A, Brady SF. MacIntyre LW, et al. Among authors: koirala b. Org Lett. 2024 May 31;26(21):4433-4437. doi: 10.1021/acs.orglett.4c00999. Epub 2024 May 20. Org Lett. 2024. PMID: 38767867

2

Discovery of Paenibacillaceae Family Gram-Negative-Active Cationic Lipopeptide Antibiotics Using Evolution-Guided Chemical Synthesis.

Wang Z, Koirala B, Hernandez Y, Brady SF. Wang Z, et al. Among authors: koirala b. Org Lett. 2022 Jul 15;24(27):4943-4948. doi: 10.1021/acs.orglett.2c01879. Epub 2022 Jul 1. Org Lett. 2022. PMID: 35776528 Free PMC article.

3

Synthetic-Bioinformatic Natural Product Antibiotics with Diverse Modes of Action.

Chu J, Koirala B, Forelli N, Vila-Farres X, Ternei MA, Ali T, Colosimo DA, Brady SF. Chu J, et al. Among authors: koirala b. J Am Chem Soc. 2020 Aug 19;142(33):14158-14168. doi: 10.1021/jacs.0c04376. Epub 2020 Aug 11. J Am Chem Soc. 2020. PMID: 32697091 Free PMC article.

4

Biosynthetic Interrogation of Soil Metagenomes Reveals Metamarin, an Uncommon Cyclomarin Congener with Activity against Mycobacterium tuberculosis.

Li L, MacIntyre LW, Ali T, Russo R, Koirala B, Hernandez Y, Brady SF. Li L, et al. Among authors: koirala b. J Nat Prod. 2021 Apr 23;84(4):1056-1066. doi: 10.1021/acs.jnatprod.0c01104. Epub 2021 Feb 23. J Nat Prod. 2021. PMID: 33621083 Free PMC article.

5

Synthesis and evaluation of dual-action kanglemycin-fluoroquinolone hybrid antibiotics.

Peek J, Koirala B, Brady SF. Peek J, et al. Among authors: koirala b. Bioorg Med Chem Lett. 2022 Feb 1;57:128484. doi: 10.1016/j.bmcl.2021.128484. Epub 2021 Nov 30. Bioorg Med Chem Lett. 2022. PMID: 34861348 Free PMC article.

6

Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens.

Li L, Koirala B, Hernandez Y, MacIntyre LW, Ternei MA, Russo R, Brady SF. Li L, et al. Among authors: koirala b. Nat Microbiol. 2022 Jan;7(1):120-131. doi: 10.1038/s41564-021-01013-8. Epub 2021 Dec 23. Nat Microbiol. 2022. PMID: 34949828 Free PMC article.

7

Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance.

Wang Z, Koirala B, Hernandez Y, Zimmerman M, Brady SF. Wang Z, et al. Among authors: koirala b. Science. 2022 May 27;376(6596):991-996. doi: 10.1126/science.abn4213. Epub 2022 May 26. Science. 2022. PMID: 35617397 Free PMC article.

8

A naturally inspired antibiotic to target multidrug-resistant pathogens.

Wang Z, Koirala B, Hernandez Y, Zimmerman M, Park S, Perlin DS, Brady SF. Wang Z, et al. Among authors: koirala b. Nature. 2022 Jan;601(7894):606-611. doi: 10.1038/s41586-021-04264-x. Epub 2022 Jan 5. Nature. 2022. PMID: 34987225 Free PMC article.

9

Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals.

Piscotta FJ, Hoffmann HH, Choi YJ, Small GI, Ashbrook AW, Koirala B, Campbell EA, Darst SA, Rice CM, Brady SF. Piscotta FJ, et al. Among authors: koirala b. mSphere. 2021 Dec 22;6(6):e0071121. doi: 10.1128/mSphere.00711-21. Epub 2021 Dec 1. mSphere. 2021. PMID: 34851166 Free PMC article.

10

Defining the hydrophobic interactions that drive competence stimulating peptide (CSP)-ComD binding in Streptococcus pneumoniae.

Koirala B, Hillman RA, Tiwold EK, Bertucci MA, Tal-Gan Y. Koirala B, et al. Beilstein J Org Chem. 2018 Jul 16;14:1769-1777. doi: 10.3762/bjoc.14.151. eCollection 2018. Beilstein J Org Chem. 2018. PMID: 30112082 Free PMC article.

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