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Acanthamoeba castellanii trophozoites need oxygen for normal functioning and lipids are their preferred substrate, offering new possibilities for treatment.
Sarink MJ, Mykytyn AZ, Jedidi A, Houweling M, Brouwers JF, Ruijter G, Verbon A, van Hellemond JJ, Tielens AGM. Sarink MJ, et al. Among authors: mykytyn az. Int J Parasitol. 2024 Oct 26:S0020-7519(24)00187-5. doi: 10.1016/j.ijpara.2024.10.004. Online ahead of print. Int J Parasitol. 2024. PMID: 39490506 Free article.
Safety, immunogenicity, and optimal dosing of a modified vaccinia Ankara-based vaccine against MERS-CoV in healthy adults: a phase 1b, double-blind, randomised placebo-controlled clinical trial.
Raadsen MP, Dahlke C, Fathi A, Hardtke S, Klüver M, Krähling V, Gerresheim GK, Mayer L, Mykytyn AZ, Weskamm LM, Zoran T, van Gorp ECM, Sutter G, Becker S, Haagmans BL, Addo MM; MVA-MERS-S_DF-1 Study group. Raadsen MP, et al. Among authors: mykytyn az. Lancet Infect Dis. 2024 Oct 7:S1473-3099(24)00423-7. doi: 10.1016/S1473-3099(24)00423-7. Online ahead of print. Lancet Infect Dis. 2024. PMID: 39389076
Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays.
Mühlemann B, Wilks SH, Baracco L, Bekliz M, Carreño JM, Corman VM, Davis-Gardner ME, Dejnirattisai W, Diamond MS, Douek DC, Drosten C, Eckerle I, Edara VV, Ellis M, Fouchier RAM, Frieman M, Godbole S, Haagmans B, Halfmann PJ, Henry AR, Jones TC, Katzelnick LC, Kawaoka Y, Kimpel J, Krammer F, Lai L, Liu C, Lusvarghi S, Meyer B, Mongkolsapaya J, Montefiori DC, Mykytyn A, Netzl A, Pollett S, Rössler A, Screaton GR, Shen X, Sigal A, Simon V, Subramanian R, Supasa P, Suthar MS, Türeli S, Wang W, Weiss CD, Smith DJ. Mühlemann B, et al. Among authors: mykytyn a. Sci Transl Med. 2024 May 15;16(747):eadl1722. doi: 10.1126/scitranslmed.adl1722. Epub 2024 May 15. Sci Transl Med. 2024. PMID: 38748773
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models.
Kaiser FK, Hernandez MG, Krüger N, Englund E, Du W, Mykytyn AZ, Raadsen MP, Lamers MM, Rodrigues Ianiski F, Shamorkina TM, Snijder J, Armando F, Beythien G, Ciurkiewicz M, Schreiner T, Gruber-Dujardin E, Bleyer M, Batura O, Erffmeier L, Hinkel R, Rocha C, Mirolo M, Drabek D, Bosch BJ, Emalfarb M, Valbuena N, Tchelet R, Baumgärtner W, Saloheimo M, Pöhlmann S, Grosveld F, Haagmans BL, Osterhaus ADME. Kaiser FK, et al. Among authors: mykytyn az. Nat Commun. 2024 Mar 14;15(1):2319. doi: 10.1038/s41467-024-46443-0. Nat Commun. 2024. PMID: 38485931 Free PMC article.
Fangchinoline inhibits SARS-CoV-2 and MERS-CoV entry.
Sadhu S, Dandotiya J, Dalal R, Khatri R, Mykytyn AZ, Batra A, Kaur M, Chandwaskar R, Singh V, Kamboj A, Srivastava M, Mani S, Asthana S, Samal S, Rizvi ZA, Salunke DB, Haagmans BL, Awasthi A. Sadhu S, et al. Among authors: mykytyn az. Antiviral Res. 2023 Dec;220:105743. doi: 10.1016/j.antiviral.2023.105743. Epub 2023 Nov 8. Antiviral Res. 2023. PMID: 37949319
Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera.
Mühlemann B, Wilks SH, Baracco L, Bekliz M, Carreño JM, Corman VM, Davis-Gardner ME, Dejnirattisai W, Diamond MS, Douek DC, Drosten C, Eckerle I, Edara VV, Ellis M, Fouchier RAM, Frieman M, Godbole S, Haagmans B, Halfmann PJ, Henry AR, Jones TC, Katzelnick LC, Kawaoka Y, Kimpel J, Krammer F, Lai L, Liu C, Lusvarghi S, Meyer B, Mongkolsapaya J, Montefiori DC, Mykytyn A, Netzl A, Pollett S, Rössler A, Screaton GR, Shen X, Sigal A, Simon V, Subramanian R, Supasa P, Suthar M, Türeli S, Wang W, Weiss CD, Smith DJ. Mühlemann B, et al. Among authors: mykytyn a. bioRxiv [Preprint]. 2023 Sep 27:2023.09.27.559689. doi: 10.1101/2023.09.27.559689. bioRxiv. 2023. PMID: 37808679 Free PMC article. Preprint.
Antigenic evolution of SARS coronavirus 2.
Mykytyn AZ, Fouchier RA, Haagmans BL. Mykytyn AZ, et al. Curr Opin Virol. 2023 Oct;62:101349. doi: 10.1016/j.coviro.2023.101349. Epub 2023 Aug 28. Curr Opin Virol. 2023. PMID: 37647851 Free article. Review.
SARS-CoV-2 ORF8 accessory protein is a virulence factor.
Bello-Perez M, Hurtado-Tamayo J, Mykytyn AZ, Lamers MM, Requena-Platek R, Schipper D, Muñoz-Santos D, Ripoll-Gómez J, Esteban A, Sánchez-Cordón PJ, Enjuanes L, Haagmans BL, Sola I. Bello-Perez M, et al. Among authors: mykytyn az. mBio. 2023 Oct 31;14(5):e0045123. doi: 10.1128/mbio.00451-23. Epub 2023 Aug 25. mBio. 2023. PMID: 37623322 Free PMC article.
29 results