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A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis.
Tricarico PM, Gratton R, Dos Santos-Silva CA, de Moura RR, Ura B, Sommella E, Campiglia P, Del Vecchio C, Moltrasio C, Berti I, D'Adamo AP, Elsherbini AMA, Staudenmaier L, Chersi K, Boniotto M, Krismer B, Schittek B, Crovella S. Tricarico PM, et al. Among authors: schittek b. Front Immunol. 2022 Dec 5;13:1060547. doi: 10.3389/fimmu.2022.1060547. eCollection 2022. Front Immunol. 2022. PMID: 36544771 Free PMC article.
The epidermal lipid barrier in microbiome-skin interaction.
Kengmo Tchoupa A, Kretschmer D, Schittek B, Peschel A. Kengmo Tchoupa A, et al. Among authors: schittek b. Trends Microbiol. 2023 Jul;31(7):723-734. doi: 10.1016/j.tim.2023.01.009. Epub 2023 Feb 21. Trends Microbiol. 2023. PMID: 36822953 Review.
Targeting Gαi2 in neutrophils protects from myocardial ischemia reperfusion injury.
Köhler D, Leiss V, Beichert L, Killinger S, Grothe D, Kushwaha R, Schröter A, Roslan A, Eggstein C, Focken J, Granja T, Devanathan V, Schittek B, Lukowski R, Weigelin B, Rosenberger P, Nürnberg B, Beer-Hammer S. Köhler D, et al. Among authors: schittek b. Basic Res Cardiol. 2024 Oct;119(5):717-732. doi: 10.1007/s00395-024-01057-x. Epub 2024 May 30. Basic Res Cardiol. 2024. PMID: 38811421 Free PMC article.
Skin Cancer Induction by the Antimycotic Drug Voriconazole Is Caused by Impaired DNA Damage Detection Due to Chromatin Compaction.
Giovannini S, Weibel L, Schittek B, Sinnberg T, Schaller M, Lemberg C, Fehrenbacher B, Biesemeier A, Nordin R, Ivanova I, Kurz B, Svilenska T, Berger C, Bourquin JP, Kulik A, Fassihi H, Lehmann A, Sarkany R, Kobert N, van Toorn M, Marteijn JA, French LE, Rocken M, Vermeulen W, Kamenisch Y, Berneburg M. Giovannini S, et al. Among authors: schittek b. J Invest Dermatol. 2024 Nov;144(11):2465-2476. doi: 10.1016/j.jid.2024.03.050. Epub 2024 Jul 22. J Invest Dermatol. 2024. PMID: 39047967
naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation.
Bork F, Greve CL, Youn C, Chen S, N C Leal V, Wang Y, Fischer B, Nasri M, Focken J, Scheurer J, Engels P, Dubbelaar M, Hipp K, Zalat B, Szolek A, Wu MJ, Schittek B, Bugl S, Kufer TA, Löffler MW, Chamaillard M, Skokowa J, Kramer D, Archer NK, Weber ANR. Bork F, et al. Among authors: schittek b. EMBO Rep. 2024 Jul;25(7):2914-2949. doi: 10.1038/s44319-024-00150-5. Epub 2024 May 23. EMBO Rep. 2024. PMID: 38783164 Free PMC article.
Dormancy of cutaneous melanoma.
Singvogel K, Schittek B. Singvogel K, et al. Among authors: schittek b. Cancer Cell Int. 2024 Feb 28;24(1):88. doi: 10.1186/s12935-024-03278-5. Cancer Cell Int. 2024. PMID: 38419052 Free PMC article. Review.
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