Risch N - Search Results

1

Identification of the Molecular Components of Enhancer-Mediated Gene Expression Variation in Multiple Tissues Regulating Blood Pressure.

Yaacov O, Mathiyalagan P, Berk-Rauch HE, Ganesh SK, Zhu L, Hoffmann TJ, Iribarren C, Risch N, Lee D, Chakravarti A. Yaacov O, et al. Among authors: risch n. Hypertension. 2024 Jul;81(7):1500-1510. doi: 10.1161/HYPERTENSIONAHA.123.22538. Epub 2024 May 15. Hypertension. 2024. PMID: 38747164

2

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

Hoffmann TJ, Ehret GB, Nandakumar P, Ranatunga D, Schaefer C, Kwok PY, Iribarren C, Chakravarti A, Risch N. Hoffmann TJ, et al. Among authors: risch n. Nat Genet. 2017 Jan;49(1):54-64. doi: 10.1038/ng.3715. Epub 2016 Nov 14. Nat Genet. 2017. PMID: 27841878 Free PMC article.

3

Analysis of putative cis-regulatory elements regulating blood pressure variation.

Nandakumar P, Lee D, Hoffmann TJ, Ehret GB, Arking D, Ranatunga D, Li M, Grove ML, Boerwinkle E, Schaefer C, Kwok PY, Iribarren C, Risch N, Chakravarti A. Nandakumar P, et al. Among authors: risch n. Hum Mol Genet. 2020 Jul 21;29(11):1922-1932. doi: 10.1093/hmg/ddaa098. Hum Mol Genet. 2020. PMID: 32436959 Free PMC article.

4

A large genome-wide association study of QT interval length utilizing electronic health records.

Hoffmann TJ, Lu M, Oni-Orisan A, Lee C, Risch N, Iribarren C. Hoffmann TJ, et al. Among authors: risch n. Genetics. 2022 Nov 30;222(4):iyac157. doi: 10.1093/genetics/iyac157. Genetics. 2022. PMID: 36271874 Free PMC article.

5

The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change.

Oni-Orisan A, Haldar T, Ranatunga DK, Medina MW, Schaefer C, Krauss RM, Iribarren C, Risch N, Hoffmann TJ. Oni-Orisan A, et al. Among authors: risch n. NPJ Genom Med. 2020 Jan 16;5:1. doi: 10.1038/s41525-019-0109-4. eCollection 2020. NPJ Genom Med. 2020. PMID: 31969989 Free PMC article.

6

Effect of SLCO1B1 T521C on Statin-Related Myotoxicity With Use of Lovastatin and Atorvastatin.

Lu B, Sun L, Seraydarian M, Hoffmann TJ, Medina MW, Risch N, Iribarren C, Krauss RM, Oni-Orisan A. Lu B, et al. Among authors: risch n. Clin Pharmacol Ther. 2021 Sep;110(3):733-740. doi: 10.1002/cpt.2337. Epub 2021 Jul 23. Clin Pharmacol Ther. 2021. PMID: 34114646 Free PMC article.

7

Polygenic Risk Score and Statin Relative Risk Reduction for Primary Prevention of Myocardial Infarction in a Real-World Population.

Oni-Orisan A, Haldar T, Cayabyab MAS, Ranatunga DK, Hoffmann TJ, Iribarren C, Krauss RM, Risch N. Oni-Orisan A, et al. Among authors: risch n. Clin Pharmacol Ther. 2022 Nov;112(5):1070-1078. doi: 10.1002/cpt.2715. Epub 2022 Aug 24. Clin Pharmacol Ther. 2022. PMID: 35862449 Free PMC article.

8

Characterization of Statin Low-Density Lipoprotein Cholesterol Dose-Response Using Electronic Health Records in a Large Population-Based Cohort.

Oni-Orisan A, Hoffmann TJ, Ranatunga D, Medina MW, Jorgenson E, Schaefer C, Krauss RM, Iribarren C, Risch N. Oni-Orisan A, et al. Among authors: risch n. Circ Genom Precis Med. 2018 Sep;11(9):e002043. doi: 10.1161/CIRCGEN.117.002043. Circ Genom Precis Med. 2018. PMID: 30354326 Free PMC article.

9

Torsade de pointes: A nested case-control study in an integrated healthcare delivery system.

Mantri N, Lu M, Zaroff JG, Risch N, Hoffmann T, Oni-Orisan A, Lee C, Iribarren C. Mantri N, et al. Among authors: risch n. Ann Noninvasive Electrocardiol. 2022 Jan;27(1):e12888. doi: 10.1111/anec.12888. Epub 2021 Sep 21. Ann Noninvasive Electrocardiol. 2022. PMID: 34547155 Free PMC article.

10

A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records.

Hoffmann TJ, Keats BJ, Yoshikawa N, Schaefer C, Risch N, Lustig LR. Hoffmann TJ, et al. Among authors: risch n. PLoS Genet. 2016 Oct 20;12(10):e1006371. doi: 10.1371/journal.pgen.1006371. eCollection 2016 Oct. PLoS Genet. 2016. PMID: 27764096 Free PMC article.

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