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Page 1
A mutation in the PRKAR1B gene drives pathological mechanisms of neurodegeneration across species.
Benjamin-Zukerman T, Shimon G, Gaine ME, Dakwar A, Peled N, Aboraya M, Masri-Ismail A, Safadi-Safa R, Solomon M, Lev-Ram V, Rissman RA, Mayrhofer JE, Raffeiner A, Mol MO, Argue BMR, McCool S, Doan B, van Swieten J, Stefan E, Abel T, Ilouz R. Benjamin-Zukerman T, et al. Among authors: mayrhofer je. Brain. 2024 Nov 4;147(11):3890-3905. doi: 10.1093/brain/awae154. Brain. 2024. PMID: 38743596 Free PMC article.
The many faces of compartmentalized PKA signalosomes.
Torres-Quesada O, Mayrhofer JE, Stefan E. Torres-Quesada O, et al. Among authors: mayrhofer je. Cell Signal. 2017 Sep;37:1-11. doi: 10.1016/j.cellsig.2017.05.012. Epub 2017 May 18. Cell Signal. 2017. PMID: 28528970 Free article. Review.
Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling.
Bachmann VA, Mayrhofer JE, Ilouz R, Tschaikner P, Raffeiner P, Röck R, Courcelles M, Apelt F, Lu TW, Baillie GS, Thibault P, Aanstad P, Stelzl U, Taylor SS, Stefan E. Bachmann VA, et al. Among authors: mayrhofer je. Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7786-91. doi: 10.1073/pnas.1608061113. Epub 2016 Jun 28. Proc Natl Acad Sci U S A. 2016. PMID: 27357676 Free PMC article.
Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies.
Mayrhofer JE, Enzler F, Feichtner A, Röck R, Fleischmann J, Raffeiner A, Tschaikner P, Ogris E, Huber RG, Hartl M, Schneider R, Troppmair J, Torres-Quesada O, Stefan E. Mayrhofer JE, et al. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31105-31113. doi: 10.1073/pnas.2012150117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229534 Free PMC article.