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Traditional Japanese medicine Kamikihito ameliorates sucrose preference, chronic inflammation and obesity induced by a high fat diet in middle-aged mice.
Maejima Y, Yokota S, Yamachi M, Misaka S, Ono T, Oizumi H, Mizuno K, Hidema S, Nishimori K, Aoyama M, de Wet H, Shimomura K. Maejima Y, et al. Among authors: de wet h. Front Endocrinol (Lausanne). 2024 Apr 29;15:1387964. doi: 10.3389/fendo.2024.1387964. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38742193 Free PMC article.
The release of GLP-1 from gut L cells is inhibited by low extracellular pH.
Garbutt P, Cyranka M, Michl J, Maejima Y, Vedovato N, Shimomura K, Swietach P, de Wet H. Garbutt P, et al. Among authors: de wet h. Obesity (Silver Spring). 2024 Oct;32(10):1819-1824. doi: 10.1002/oby.24125. Epub 2024 Sep 5. Obesity (Silver Spring). 2024. PMID: 39238194 Free PMC article.
Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretion.
Veprik A, Denwood G, Liu D, Bany Bakar R, Morfin V, McHugh K, Tebeka NN, Vetterli L, Yonova-Doing E, Gribble F, Reimann F, Hoehn KL, Hemsley PA, Ahnfelt-Rønne J, Rorsman P, Zhang Q, de Wet H, Cantley J. Veprik A, et al. Among authors: de wet h. Commun Biol. 2022 Mar 18;5(1):238. doi: 10.1038/s42003-022-03170-w. Commun Biol. 2022. PMID: 35304577 Free PMC article.
Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with 'refractoriness to treatment': a cohort study.
Henriquez DDCA, Gillissen A, Smith SM, Cramer RA, van den Akker T, Zwart JJ, van Roosmalen JJM, Bloemenkamp KWM, van der Bom JG; TeMpOH-1 study group. Henriquez DDCA, et al. BMC Pregnancy Childbirth. 2019 Oct 17;19(1):361. doi: 10.1186/s12884-019-2499-9. BMC Pregnancy Childbirth. 2019. PMID: 31623631 Free PMC article.
Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1.
Cyranka M, Veprik A, McKay EJ, van Loon N, Thijsse A, Cotter L, Hare N, Saibudeen A, Lingam S, Pires E, Larraufie P, Reimann F, Gribble F, Stewart M, Bentley E, Lear P, McCullagh J, Cantley J, Cox RD, de Wet H. Cyranka M, et al. Among authors: de wet h. Obesity (Silver Spring). 2019 Aug;27(8):1292-1304. doi: 10.1002/oby.22521. Obesity (Silver Spring). 2019. PMID: 31338999 Free PMC article.
65 results