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High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2.
Almeida L, van Roey R, Patente TA, Otto F, Veldhuizen T, Ghorasaini M, van Diepen A, Schramm G, Liu J, Idborg H, Korotkova M, Jakobsson PJ, Giera M, Hokke CH, Everts B. Almeida L, et al. Among authors: hokke ch. Front Immunol. 2024 Apr 29;15:1372927. doi: 10.3389/fimmu.2024.1372927. eCollection 2024. Front Immunol. 2024. PMID: 38742105 Free PMC article.
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses.
Everts B, Perona-Wright G, Smits HH, Hokke CH, van der Ham AJ, Fitzsimmons CM, Doenhoff MJ, van der Bosch J, Mohrs K, Haas H, Mohrs M, Yazdanbakhsh M, Schramm G. Everts B, et al. Among authors: hokke ch. J Exp Med. 2009 Aug 3;206(8):1673-80. doi: 10.1084/jem.20082460. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635864 Free PMC article.
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor.
Everts B, Hussaarts L, Driessen NN, Meevissen MH, Schramm G, van der Ham AJ, van der Hoeven B, Scholzen T, Burgdorf S, Mohrs M, Pearce EJ, Hokke CH, Haas H, Smits HH, Yazdanbakhsh M. Everts B, et al. Among authors: hokke ch. J Exp Med. 2012 Sep 24;209(10):1753-67, S1. doi: 10.1084/jem.20111381. Epub 2012 Sep 10. J Exp Med. 2012. PMID: 22966004 Free PMC article.
The Schistosoma mansoni lipidome: Leads for immunomodulation.
Giera M, Kaisar MMM, Derks RJE, Steenvoorden E, Kruize YCM, Hokke CH, Yazdanbakhsh M, Everts B. Giera M, et al. Among authors: hokke ch. Anal Chim Acta. 2018 Dec 11;1037:107-118. doi: 10.1016/j.aca.2017.11.058. Epub 2017 Nov 27. Anal Chim Acta. 2018. PMID: 30292284 Free article.
182 results